2103-90-4Relevant articles and documents
Photo-sensitized oxy-thiocyanation of terminal alkynes/1,3-aryldienes and their one-pot conversion to 2-hydroxy 4-substituted aryl thiazoles
Gullapalli, Kumaraswamy,Vijaykumar, Swargam
, p. 2232 - 2241 (2019/02/27)
A regioselective visible light induced synthesis of aryl α-thiocyano ketones/thiocyano alcohols from activated terminal aryl alkynes and aryl 1,3-conjugated dienes was achieved. This mild and non-metallic oxidation is exclusively driven by benign ambient air in the presence of an organic photo-catalyst and NH4SCN. This protocol was also demonstrated at the 5 mmol scale for the synthesis of potentially therapeutic 2-hydroxy 4-substituted arylthiazoles in good yields, signifying its amenability for large-scale application.
A correlative IR, MS, 1H, 13C and 15 NMR and theoretical study of 4-arylthiazol-2(3H)-ones
Pihlaja, Kalevi,Ovcharenko, Vladimir,Kolehmainen, Erkki,Laihia, Katri,Fabian, Walter M.F.,Dehne, Heinz,Perjessy, Alexander,Kleist, Marion,Teller, Joachim,Sustekova, Zora
, p. 329 - 336 (2007/10/03)
Sixteen 4-arylthiazol-2(3H)-ones (3) were synthesised by cyclisation of α-thiocyanatoacetophenones (1) in acid solution. They appear to prefer greatly the oxo tautomeric forms. In CCI4 solution an equilibrium between the free C=O bond and a "di
