210536-89-3

Basic information

• Product Name: N-(3,5-dimethylphenyl) benzophenone hydrazone
• Synonyms: N-(3,5-dimethylphenyl) benzophenone hydrazone
• CAS NO: 210536-89-3
• Molecular Weight: 300.403
• Mol File: 210536-89-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3,5-dimethylphenyl) benzophenone hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,5-dimethylphenyl) benzophenone hydrazone(210536-89-3)
• EPA Substance Registry System: N-(3,5-dimethylphenyl) benzophenone hydrazone(210536-89-3)

Safety Data

• Hazardous Substances Data: 210536-89-3(Hazardous Substances Data)

Upstream product

• 5350-57-2 benzophenone hydrazone 
• 556-96-7 5-bromo-1,3-xylene 
• 22445-41-6 3,5-dimethylphenyl iodide 

Downstream Products

• 95264-40-7 4,6-dimethylindole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds

The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or amine moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In additional embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between a nitrogen atom of an acyl hydrazine and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of a nitrogen-containing heteroaromatic, e.g., indole, pyrazole, and indazole, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-oxygen bond between the oxygen atom of an alcohol and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. The present invention also relates to copper-catalyzed methods of forming a carbon-carbon bond between a reactant comprising a nucleophilic carbon atom, e.g., an enolate or malonate anion, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. Importantly, all the methods of the present invention are relatively inexpensive to practice due to the low cost of the copper comprised by the catalysts.

A palladium-catalyzed method for the preparation of indoles via the Fischer indole synthesis

A Pd-catalyzed method for the preparation of N-aryl benzophenone hydrazones 4 is described. The use of a Pd/BINAP-based catalyst provides hydrazones 4 in good yields. Using 0.1 mol % of a Pd/9,9-dimethyl-4,5- bis(diphenylphosphino)xanthene (Xantphos) cata