21064-18-6

Basic information

• Product Name: H-GLU-ALA-OH
• Synonyms: C8H14N2O5;H-GLU-ALA-OH;L-GLUTAMYL-L-ALANINE;L-ALPHA-GLUTAMYL-L-ALANINE;glu-ala;4-amino-5-[(1-hydroxy-1-oxopropan-2-yl)amino]-5-oxopentanoic acid;Glutamylalanine;L-A-GLUTAMYL-L-ALANINE
• CAS NO: 21064-18-6
• Molecular Formula: C8H14N2O5
• Molecular Weight: 218.21
• Product Categories: Amino Acid Derivatives
• Mol File: 21064-18-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 566.5 °C at 760 mmHg
• Flash Point: 296.4 °C
• Appearance: /
• Density: 1.362 g/cm³
• Vapor Pressure: 2.59E-14mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly), Water (Slightly, Sonicated)
• PKA: 3.10±0.10(Predicted)
• CAS DataBase Reference: H-GLU-ALA-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-GLU-ALA-OH(21064-18-6)
• EPA Substance Registry System: H-GLU-ALA-OH(21064-18-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 21064-18-6(Hazardous Substances Data)

Usage

Description

H-GLU-ALA-OH, also known as 4-Amino-N-(1-carboxyethyl)-glutaramic Acid, is a dipeptide formed from L-alpha-glutamyl and L-alanine residues. It is a compound that has been identified in biological studies, particularly in the context of kokumi substances and bacteria in fermented Thai freshwater fish.

Uses

Used in Flavor and Taste Enhancement:
H-GLU-ALA-OH is used as a flavor enhancer for its kokumi properties, which contribute to the overall taste and mouthfeel of food products. It helps to improve the perception of flavors and create a more satisfying eating experience.
Used in Pharmaceutical Applications:
H-GLU-ALA-OH is used as a pharmaceutical compound for its potential therapeutic applications. As a dipeptide, it may have implications in the development of new drugs or therapies, particularly in the areas of nutrition and metabolism.
Used in Research and Development:
H-GLU-ALA-OH is used as a research compound for studying its properties and potential applications in various industries, such as food science, pharmaceuticals, and biotechnology. Its unique structure and properties make it an interesting subject for further investigation and development.
Used in Food Industry:
H-GLU-ALA-OH is used as an additive in the food industry for enhancing the taste and flavor of various products. Its kokumi properties can help to create a more well-rounded and satisfying taste experience for consumers.
Used in Cosmetics and Personal Care:
H-GLU-ALA-OH may be used as an ingredient in cosmetics and personal care products, where its properties could be harnessed for various applications, such as skin care or hair care products. Further research would be needed to determine its specific uses and benefits in this industry.

InChI:InChI=1/C8H14N2O5/c1-4(8(14)15)10-7(13)5(9)2-3-6(11)12/h4-5H,2-3,9H2,1H3,(H,10,13)(H,11,12)(H,14,15)

Upstream product

• 4124-76-9 N-(benzyloxycarbonyl)-L-glutamic acid anhydride 
• 5680-86-4 N-benzyloxycarbonyl-5-O-benzyl-L-glutamic acid 
• 98561-55-8 N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-alanine ethyl ester 
• 96467-84-4 N-(O-benzyl-N-benzyloxycarbonyl-L-α-glutamyl)-L-alanine benzyl ester 
• 98032-38-3 N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-alanine 

Downstream Products

• 56-41-7 L-alanin 
• 56-86-0 L-glutamic acid 

Relevant articles and documents

PEPTIDE COMPOUNDS AND METHODS OF USING PEPTIDE COMPOUNDS TO TREAT CONDITIONS AFFECTING THE CARDIAC, PULMONARY, AND NERVOUS SYSTEMS

The present invention provides a method of treating or preventing diseases or conditions affecting the cardiac, pulmonary and/or nervous systems in a subject using peptide compounds. The methods of the invention are useful for the treatment and prevention of a variety of disorders or conditions including, without limitation, ischemia, stroke, pulmonary diseases, allergic reactions, physical trauma to pulmonary tissues, exposure to harmful entities in the environment, and smoking.