210691-68-2

Basic information

• Product Name: (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methyl-1-triphenylmethyloxypentane
• Synonyms: (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methyl-1-triphenylmethyloxypentane
• CAS NO: 210691-68-2
• Molecular Weight: 514.824
• Mol File: 210691-68-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methyl-1-triphenylmethyloxypentane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methyl-1-triphenylmethyloxypentane(210691-68-2)
• EPA Substance Registry System: (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methyl-1-triphenylmethyloxypentane(210691-68-2)

Safety Data

• Hazardous Substances Data: 210691-68-2(Hazardous Substances Data)

Upstream product

• 210691-66-0 Ethyl (2R,3R,4S)-2-allyl-4-(tert-butyldimethylsilyloxy)-3-methylpentanoate 
• 210691-65-9 Ethyl (3R,4S)-4-(tert-butyldimethylsilyloxy)-3-methylpentanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 135614-57-2 (2S)-2-[tert-butyl(dimethyl)silyl]oxypropan-1-ol 
• 105198-38-7 ethyl (S)-2-(tert-butyldimethylsilyloxy)propanoate 
• 105198-40-1 ethyl (2E,4S)-4-<(tert-butyldimethylsilyl)oxy>-2-pentenoate 
• 76-83-5 trityl chloride 
• 210691-67-1 (2R,3R,4S)-2-Allyl-4-(tert-butyldimethylsilyloxy)-3-methylpentanol 

Downstream Products

• 210691-70-6 (2R,3R,4S)-2-Allyl-4-(4-chlorobenzoyloxy)-3-methyl-1-triphenylmethyloxypentan-4-ol 
• 210691-69-3 (2R,3R,4S)-2-Allyl-3-methyl-1-triphenylmethyloxypentan-4-ol 

Relevant articles and documents

Synthetic studies on the pederin family of antitumour agents. Syntheses of mycalamide B, theopederin D and pederin

The synthesis of mycalamide B, theopederin D and pederin, which are antitumour agents was discussed. All three compounds were prepared from 6-lithio-2,3-dimethyl-4-phenylselenomethyl-3,4-dihydro-2H-pyran and 2-(3-chloropropyl)-3,3-dimethyl-3,4-dihydro-2H-pyran-4-one. Ground state conformational models were proposed to explain the stereoselectivity of the reactions. The absolute and relative stereochemistry of the compounds has been established by X-ray crystallography and NMR studies.