210963-56-7

Basic information

• Product Name: benzyl (3R)-tert-butoxycarbonylamino-4-(5-cyano-2-iodophenoxy)butyric acid
• Synonyms: benzyl (3R)-tert-butoxycarbonylamino-4-(5-cyano-2-iodophenoxy)butyric acid
• CAS NO: 210963-56-7
• Molecular Weight: 536.366
• Mol File: 210963-56-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl (3R)-tert-butoxycarbonylamino-4-(5-cyano-2-iodophenoxy)butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (3R)-tert-butoxycarbonylamino-4-(5-cyano-2-iodophenoxy)butyric acid(210963-56-7)
• EPA Substance Registry System: benzyl (3R)-tert-butoxycarbonylamino-4-(5-cyano-2-iodophenoxy)butyric acid(210963-56-7)

Safety Data

• Hazardous Substances Data: 210963-56-7(Hazardous Substances Data)

Upstream product

• 10465-78-8 diamide 
• 182748-72-7 (R)-3-((tert-butoxycarbonyl)amino)-4-hydroxybutyric acid benzyl ester 
• 210962-75-7 3-hydroxy-4-iodobenzonitrile 
• 51186-58-4 4-benzyl Boc-D-aspartate 

Downstream Products

• 538335-94-3 methyl 2-acetamido-3-[2-(2R)-2-[4-(1-tert-butoxycarbonylpiperidyl-4-oxy)benzoylamino-3-benzyloxycarbonylpropoxy]-4-cyanophenyl]acrylate 
• 538335-97-6 methyl 2-acetamido-3-[4-amidino-2-[(2R)-3-ethoxycarbonyl-2-[4-(piperidyl-4-oxy)benzoylamino]propoxy]phenyl]acrylate 
• 538335-95-4 methyl 2-acetamido-3-[2-[(R)-2-[1-(4-pyridyl)piperidine-4-carbonyl]amino-3-benzyloxycarbonylpropoxy]-4-cyanophenyl]acrylate 
• 538335-87-4 methyl 2-acetamido-3-[(2-butoxycarbonylcarbonylamino-3-benzyloxycarbonylpropoxy)-4-cyanophenyl]acrylate 

Relevant articles and documents

Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors: (2-substituted-4-amidinophenyl)pyruvic and -propionic acids

An inhibitor of factor Xa (fXa), the m-substituted benzamidine AXC1578 (1a), was structurally modified with the aim of increasing its potency. In particular, pyruvic acid and propionic acid substituents were incorporated into the P1 benzamidine moiety to