210992-77-1

Basic information

• Product Name: 3-chloro-5-(4-methoxybenzyloxy)bromobenzene
• Synonyms: 3-chloro-5-(4-methoxybenzyloxy)bromobenzene
• CAS NO: 210992-77-1
• Molecular Weight: 327.605
• Mol File: 210992-77-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloro-5-(4-methoxybenzyloxy)bromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-(4-methoxybenzyloxy)bromobenzene(210992-77-1)
• EPA Substance Registry System: 3-chloro-5-(4-methoxybenzyloxy)bromobenzene(210992-77-1)

Safety Data

• Hazardous Substances Data: 210992-77-1(Hazardous Substances Data)

Upstream product

• 33863-76-2 1-bromo-3-chloro-5-fluorobenzene 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 56962-04-0 3-bromo-5-chlorophenol 

Relevant articles and documents

A synthesis of 3,5-disubstituted phenols

Robust and scalable syntheses of some synthetically useful 3,5- disubstituted phenols are presented. The process involves the selective displacement of a halogen by nucleophilic aromatic substitution using a preformed mixture of potassium tert-butoxide and p-methoxybenzyl alcohol (PMB-OH), followed by deprotection of the PMB ether with acid in the presence of 1,3-dimethoxybenzene. These processes have been demonstrated on kilogramscale, providing crystalline phenols in good yield and high purity.