2110-18-1

Basic information

• Product Name: 2-(3-PHENYLPROPYL)PYRIDINE
• Synonyms: 2-(3-phenylpropyl)-pyridin;AKOS 90304;1-PHENYL-3-(2-PYRIDYL)PROPANE;2-(3-PHENYLPROPYL)PYRIDINE;FEMA 3751;FEMA NUMBER 3751;2-(3-PHENYLPROPYL)PYRIDINE 97+%;CORPS RACINE
• CAS NO: 2110-18-1
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.28
• EINECS: 218-300-7
• Product Categories: Alphabetical Listings;Flavors and Fragrances;O-P
• Mol File: 2110-18-1.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 142-143 °C1 mm Hg(lit.)
• Flash Point: 212 °F
• Appearance: Clear yellow/Liquid
• Density: 1.015 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00257mmHg at 25°C
• Refractive Index: n20/D 1.56(lit.)
• PKA: 5.80±0.12(Predicted)
• CAS DataBase Reference: 2-(3-PHENYLPROPYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-PHENYLPROPYL)PYRIDINE(2110-18-1)
• EPA Substance Registry System: 2-(3-PHENYLPROPYL)PYRIDINE(2110-18-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 2
• TSCA: Yes
• Hazardous Substances Data: 2110-18-1(Hazardous Substances Data)

Usage

Description

2-(3-PHENYLPROPYL)PYRIDINE is an organic compound characterized by a clear yellow liquid appearance. It possesses a unique molecular structure that features a pyridine ring attached to a 3-phenylpropyl group, which contributes to its distinct taste and chemical properties. 2-(3-PHENYLPROPYL)PYRIDINE is known for its green, vegetative, and jalape?o pepper-like taste with some savory metallic nuances at a concentration of 1 ppm.

Uses

Used in Flavor and Fragrance Industry:
2-(3-PHENYLPROPYL)PYRIDINE is used as a flavoring agent for its unique taste characteristics, adding a green, vegetative, and jalape?o pepper-like flavor with savory metallic nuances to various food products and beverages.
Used in Chemical Research:
2-(3-PHENYLPROPYL)PYRIDINE serves as a valuable compound in chemical research, particularly in the development of new synthetic methods, the study of its reactivity, and its potential applications in the synthesis of other organic compounds.
Used in Pharmaceutical Industry:
2-(3-PHENYLPROPYL)PYRIDINE is used as an intermediate in the synthesis of various pharmaceutical compounds, owing to its unique chemical structure and properties. It may also be employed in the development of new drugs targeting specific biological pathways or receptors.
Used in Material Science:
2-(3-PHENYLPROPYL)PYRIDINE can be utilized in the development of new materials with specific properties, such as in the creation of organic semiconductors, sensors, or other advanced materials with potential applications in various industries.

InChI:InChI=1/C14H15N/c1-2-7-13(8-3-1)9-6-11-14-10-4-5-12-15-14/h1-5,7-8,10,12H,6,9,11H2

Upstream product

• 109-06-8 α-picoline 
• 100-42-5 styrene 
• 622-24-2 2-phenylethyl chloride 
• 100-69-6 2-vinylpyridine 
• 108-88-3 toluene 
• 108-86-1 bromobenzene 
• 7439-93-2 lithium 
• 103-63-9 1-phenyl-2-bromoethane 
• 100-39-0 benzyl bromide 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 694-59-7 pyridine N-oxide 
• 1379610-52-2 4,4,5,5‐tetramethyl‐2‐[5‐phenyl‐1‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)propyl]‐1,3,2‐dioxaborolane 
• 109-09-1 2-chloropyridine 
• 329685-40-7 4,4,5,5-tetramethyl-2-(3-phenylpropyl)-[1,3,2]dioxaborolane 

Downstream Products

• 56741-25-4 1-phenyl-3-(pyridin-2-yl)propan-1-one 
• 54313-85-8 3-phenyl-1-(pyridin-2-yl)propan-1-one 
• 1422450-71-2 2-[3-phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]pyridine 
• 1422450-64-3 2-benzyl-3-(pyridin-2-yl)propan-1-ol 
• 1079883-77-4 2-(3,5-dimethylphenyl)-6-(3-phenylpropyyl)-pyridine 
• 365552-55-2 4-(1-phenethyl-indolizin-2-yl)-phenol 
• 99112-96-6 2-(3-phenyl-propyl)-piperidine 
• 115145-56-7 1-methyl-2-(3-phenyl-propyl)-pyridinium; toluene-4-sulfonate 
• 116602-63-2 1-benzyl-2-(3-phenyl-propyl)-pyridinium; chloride 

Relevant articles and documents

Unlocking the Accessibility of Alkyl Radicals from Boronic Acids through Solvent-Assisted Organophotoredox Activation

Despite their prevalence in organic synthesis, the application of boronic acids (BAs) as alkyl radical precursors in visible-light-assisted photocatalyzed reactions has been limited by their high oxidation potential. This study demonstrates the prominent

Ruthenium catalyzed β-selective alkylation of vinylpyridines with aldehydes/ketonesviaN2H4mediated deoxygenative couplings

Umpolung (polarity reversal) tactics of aldehydes/ketones have greatly broadened carbonyl chemistry by enabling transformations with electrophilic reagents and deoxygenative functionalizations. Herein, we report the first ruthenium-catalyzed β-selective alkylation of vinylpyridines with both naturally abundant aromatic and aliphatic aldehyde/ketonesviaN2H4mediated deoxygenative couplings. Compared with one-electron umpolung of carbonyls to alcohols, this two-electron umpolung strategy realized reductive deoxygenation targets, which were not only applicable to the regioselective alkylation of a broad range of 2/4-alkene substituted pyridines, but also amenable to challenging 3-vinyl and steric-embedded internal pyridines as well as their analogous heterocyclic structures.

Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes

This manuscript describes the first practical benzylic dehydrogenation of electron-deficient heteroarenes, including pyridines, pyrazines, pyrimidines, pyridazines, and triazines. This transformation allows for the efficient benzylic oxidation of heteroarenes to afford heterocyclic styrenes by the action of nickel catalysis paired with an unconventional bromothiophene oxidant.