21132-01-4

Basic information

• Product Name: 4(1H)-Quinazolinone, 2,3-dihydro-2,3-diphenyl-
• CAS NO: 21132-01-4
• Molecular Formula: C20H16N2O
• Molecular Weight: 300.36
• Mol File: 21132-01-4.mol
• Article Data: 74

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 2,3-dihydro-2,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 2,3-dihydro-2,3-diphenyl-(21132-01-4)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 2,3-dihydro-2,3-diphenyl-(21132-01-4)

Safety Data

• Hazardous Substances Data: 21132-01-4(Hazardous Substances Data)

Upstream product

• 64001-48-5 2-(sulfinylamino)benzoyl chloride 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 100-52-7 benzaldehyde 
• 4424-17-3 2-aminobenzanilide 
• 103-49-1 dibenzylamine 
• 118-48-9 isatoic anhydride 
• 538-51-2 benzylidene phenylamine 
• 100-51-6 benzyl alcohol 
• 62-53-3 aniline 

Downstream Products

• 22686-82-4 2,3-diphenyl-3H-quinazolin-4-one 

Relevant articles and documents

Preparation method of medical intermediate 2, 3-diaryl-2, 3-dihydroquinazoline-4[1H]-ketone

The invention discloses a preparation method of a medical intermediate 2, 3-diaryl-2, 3-dihydroquinazoline-4[1H]-ketone, and belongs to the technical field of preparation of medical intermediates. According to the method, basic ionic liquid is adopted as a catalyst, the molar ratio of isatoic anhydride to Schiff base in the catalytic reaction is (1.0-1.3): 1, the amount of substance of the basic ionic liquid catalyst is 3-7% of the amount of substance of the used Schiff base, and the reflux reaction time is 12-18 min. Compared with other preparation methods, the method has the advantages of recyclable catalyst, simple and convenient product purification operation, high reaction raw material utilization rate, short reaction time and the like, and is convenient for industrial large-scale production.

Sustainable parts-per-million level catalysis with FeIII: One-pot cascade synthesis of 2,3-dihydroquinazolin-4(1H)-ones in water

A silica-supported iron complex has been identified as a highly active and reusable catalyst for the synthesis of medicinally important 2,3-dihydroquinazolin-4(1H)-ones. The catalyst was fully characterized by various spectroscopic analyses such as Fourie

Fe3O4@Sap/Cu(ii): An efficient magnetically recoverable green nanocatalyst for the preparation of acridine and quinazoline derivatives in aqueous media at room temperature

Saponin, as a green and available phytochemical, was immobilized on the surface of magnetite nanoparticles then doped with Cu ions (Fe3O4@Sap/Cu(ii)) and used as an efficient nanocatalyst for the synthesis of quinazoline and acridine derivatives, due to t