211506-14-8

Basic information

• Product Name: 2-fluoro-2-phenyl-1,3-propanediol
• Synonyms: 2-fluoro-2-phenyl-1,3-propanediol
• CAS NO: 211506-14-8
• Molecular Weight: 170.184
• Mol File: 211506-14-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-fluoro-2-phenyl-1,3-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-2-phenyl-1,3-propanediol(211506-14-8)
• EPA Substance Registry System: 2-fluoro-2-phenyl-1,3-propanediol(211506-14-8)

Safety Data

• Hazardous Substances Data: 211506-14-8(Hazardous Substances Data)

Upstream product

• 83-13-6 diethyl 2-phenylmalonate 
• 2802-98-4 diethyl 2-fluoro-2-phenylmalonate 

Downstream Products

• 726-99-8 Fluorofelbamate 
• 288302-42-1 Fluoro monocarbamate felbamate 
• 25451-53-0 2-phenyl-1,3-propanediol monocarbamate 
• 25451-15-4 felbamate 
• 233277-26-4 2-fluoro-3-(triisopropylsilyloxy)-2-phenyl-1-propanol 
• 233277-24-2 3-(t-butyldimethylsilyloxy)-2-fluoro-2-phenyl-1-propanol 
• 233277-16-2 3-acetoxy-2-fluoro-2-phenyl-1-propanol 

Relevant articles and documents

Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof

Disclosed is a method of making 2-substituted-2-halo-1,3-propanediols via reduction of corresponding malonate compounds. Also disclosed is a method of making 2-substituted-2-halo-1,3-dicarbamate compounds (such as halo derivatives of felbamate, including fluorofelbamate) via reduction of malonate compounds, followed by carbamoylation. Reduction of the malonate compounds is carried out using an electrophilic hydride reagent.