211630-10-3

Basic information

• Product Name: Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(4-methoxyphenyl)-
• CAS NO: 211630-10-3
• Molecular Formula: C14H11N3O2
• Molecular Weight: 253.26
• Mol File: 211630-10-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(4-methoxyphenyl)-(211630-10-3)
• EPA Substance Registry System: Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(4-methoxyphenyl)-(211630-10-3)

Safety Data

• Hazardous Substances Data: 211630-10-3(Hazardous Substances Data)

Upstream product

• 23439-87-4 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione 
• 116060-92-5 3-(4-methoxybenzoyl)-pyridine-2-carboxylic acid 
• 164463-15-4 2-(4-methoxyphenylcarbonyl)-3-pyridine carboxylic acid 
• 100-66-3 methoxybenzene 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 211630-05-6 8-(4-methoxy-phenyl)-pyrido[2,3-d][1,2]oxazin-5-one 

Downstream Products

• 862816-20-4 5-chloro-8-(4-methoxyphenyl)-pyrido[2,3-d]pyridazine 
• 862816-21-5 8-chloro-5-(4-methoxyphenyl)-pyrido[2,3-d]pyridazine 

Relevant articles and documents

NITROGENOUS FUSED HETEROAROMATIC RING DERIVATIVE

The invention provides a compound or its pharmaceutically-acceptable salt of formula (I): wherein A1 is a hydrogen, etc.; j and k are 0 or 1; is a double bond, etc.; is a double bond, etc.; one of W1 and W2 is E-O-W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1): which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.

New synthesis of pyrido[2,3-d] and [3,2-d]oxazines

N-Hydroxyquinolinimide 1 reacts with each of aromatic arnines, hydrazine hydrate and aromatic hydrocarbons to give arylcarbamoyl pyridines 2, pyrrolopyridines 3, pyridopyridazines 4 and pyridooxazinones 5 and 6. The heterocycles 5 and 6 can be transformed