21181-90-8

Basic information

• Product Name: 4-(2-benzylsulfanyl-ethyl)-pyridine
• Synonyms: 4-(2-benzylsulfanyl-ethyl)-pyridine
• CAS NO: 21181-90-8
• Molecular Weight: 229.346
• Mol File: 21181-90-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(2-benzylsulfanyl-ethyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-benzylsulfanyl-ethyl)-pyridine(21181-90-8)
• EPA Substance Registry System: 4-(2-benzylsulfanyl-ethyl)-pyridine(21181-90-8)

Safety Data

• Hazardous Substances Data: 21181-90-8(Hazardous Substances Data)

Upstream product

• 70289-28-0 4-(2-methoxyethyl)pyridine 
• 100-43-6 4-vinylpyridine 
• 100-53-8 phenylmethanethiol 
• 100-44-7 benzyl chloride 
• 6298-11-9 4-(2-mercaptoethyl)pyridinium hydrochloride 

Relevant articles and documents

KO-t-Bu Catalyzed Thiolation of β-(Hetero)arylethyl Ethers via MeOH Elimination/hydrothiolation

Herein, we describe a KO-t-Bu catalyzed thiolation of β-(hetero)arylethyl ethers through MeOH elimination to form (hetero)arylalkenes followed by anti-Markovnikov hydrothiolation to afford linear thioethers. The system works well with a variety of β-(hetero)arylethyl ethers, including electron-deficient, electron-neutral, electron-rich, and branched substrates and a range of aliphatic and aromatic thiols.

2-(4-Pyridyl)ethyl as a Protective Group for Sulfur Functionality

2-(4-Pyridyl)ethyl sulfides have been prepared from a variety of alkyl and aryl thiols and from alkyl and acyl halides.These sulfides and their corresponding sulfoxides and sulfones were each depyridylethylated by quaternization and subsequent treatment with mild base to give respectively the thiols, sulfenic acids, sulfinic acids, and sulfenamides.During one of these protection-deprotection sequences, methyl 1-octyl sulfoxide was readily converted by aerial oxidation into the corresponding sulfone.