211935-52-3

Basic information

• Product Name: (DPPF)PdMeI
• CAS NO: 211935-52-3
• Molecular Weight: 802.75
• Mol File: 211935-52-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (DPPF)PdMeI(CAS DataBase Reference)
• NIST Chemistry Reference: (DPPF)PdMeI(211935-52-3)
• EPA Substance Registry System: (DPPF)PdMeI(211935-52-3)

Safety Data

• Hazardous Substances Data: 211935-52-3(Hazardous Substances Data)

Upstream product

• 12150-46-8 1,1'-bis-(diphenylphosphino)ferrocene 
• 18115-58-7 (PPh₃)₂PdMeI 
• 590420-33-0 Pd(η2-CH2=CHCHO)(dppf) 
• 74-88-4 methyl iodide 

Downstream Products

• 213540-29-5 ((C₆H₅)2P((C₅H₄)2Fe)P(C₆H₅)2)Pd(SC(CH₃)3)(CH₃) 

Relevant articles and documents

Difluoromethylation of Alkyl Bromides and Iodides with TMSCF2H

We describe, for the first time, two protocols for direct difluoromethylation of unactivated alkyl bromides and iodides. Reactions of alkyl iodides with TMSCF2H were mediated by a copper catalyst using CsF as the activator, while reactions of less reactive alkyl bromides required a combination of palladium and a stoichiometric amount of CuI as the catalysts. Preliminary mechanistic studies of the synergistic Pd/Cu-catalyzed difluoromethylation of alkyl bromides suggest that it proceeds likely via a Pd(I)/Pd(III) catalytic cycle.