211988-86-2

Basic information

• Product Name: (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methyl-4-methylbenzenesulfonate
• Synonyms: (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methyl-4-methylbenzenesulfonate
• CAS NO: 211988-86-2
• Molecular Weight: 604.88
• Mol File: 211988-86-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methyl-4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methyl-4-methylbenzenesulfonate(211988-86-2)
• EPA Substance Registry System: (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methyl-4-methylbenzenesulfonate(211988-86-2)

Safety Data

• Hazardous Substances Data: 211988-86-2(Hazardous Substances Data)

Upstream product

• 87727-28-4 (S)-2-tert-butyl-dimethyl-silanyloxy propanal 
• 105198-38-7 ethyl (S)-2-(tert-butyldimethylsilyloxy)propanoate 
• 211988-78-2 (Z,8S)-8-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-nonen-2-one 
• 211988-79-3 (2R,3Z,8S)-8-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-nonen-2-ol 
• 327978-02-9 ethyl (4S)-4-(tert-butyl(dimethyl)silyloxy)pentanoate 
• 105198-40-1 ethyl (2E,4S)-4-<(tert-butyldimethylsilyl)oxy>-2-pentenoate 
• 74500-58-6 (4S)-4-[tert-butyl(dimethyl)silyl]oxy-1-pentanol 
• 82729-82-6 (S)-(+)-6-((tert-butyldimethylsilyl)oxy)-1-heptyne 
• 211988-84-0 (S)-8-(tert-Butyl-dimethyl-silanyloxy)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-non-3-yn-2-one 
• 74500-59-7 (4S)-4-[tert-butyl(dimethyl)silyl]oxypentyl 4-methylbenzenesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 211988-85-1 (2S,4S,6R)-6-[((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]methanol 

Downstream Products

• 211988-77-1 (1R,2Z,7S)-7-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-[(2S)-5-oxo-4-(phenylsulfonyl)tetrahydro-2-furanyl]methyl-2-octenyl 4-methoxybenzoate 
• 211988-76-0 (1S,4R,5S)-4-Benzenesulfonyl-5-[(E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-hept-1-enyl]-2-oxa-bicyclo[2.2.1]heptan-3-one 
• 211988-80-6 methyl 3-[(2R,4S,6R)-6-((Z,6S)-6-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-1-heptenyl)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl]-2-(phenylsulfonyl)propanoate 

Relevant articles and documents

Total synthesis of (+)-brefeldin A

The total synthesis of (+)-brefeldin A has been accomplished via 15 linear steps in a 7.9% overall yield from the known Weinreb amide 6. The key parts of this approach include the stereoselective construction of the cis-disubstituted hydroxycyclopentane skeleton and the direct introduction of the C1-C3 acrylate moiety using a new variant of a trans-vinylogous acyl anion equivalent.