21211-07-4Relevant articles and documents
Synthesis, characterization and biological activities of some new benzo[b]thiophene derivatives
Isloor, Arun M.,Kalluraya, Balakrishna,Sridhar Pai
experimental part, p. 825 - 830 (2010/04/04)
Benzo[b]thiophene molecules are found to be important tools in synthetic medicinal chemistry. They are of current interest due to their wide spectrum of pharmacological properties. In view of the biological activities of benzo[b]thiophene containing molecules, in this present research work, we propose the synthesis of some new benzo[b]thiophene derivatives such as thiadiazoles, oxadiazoles, pyrazolin & diaryl pyrazoles starting from 3-chlorobenzo[b]thiophene-2-carboxyl chloride. These newly synthesized compounds were characterized by elemental analyses, I.R, NMR and Mass spectral studies. Some of the selected compounds were screened for their antibacterial, antifungal and anti-inflammatory studies. Many of the molecules were found to be potent.
Benzo[b]thiophenes, Part I: Synthesis and antimicrobial activity of benzo[b]thienyl-1,3,4-oxadiazole, -1,2,4-triazoline, and -thiazoline derivatives
AboulWafa,Berto
, p. 123 - 127 (2007/10/02)
Four new series of benzo[b]thiophene derivatives bearing various thiosemicarbazide, 1,3,4-oxadiazole, 1,2,4-triazoline, and thiazoline moieties have been synthesized and evaluated for antimicrobial activity.