21236-00-0

Basic information

• Product Name: Furan, 2-[1,1'-biphenyl]-4-yl-
• CAS NO: 21236-00-0
• Molecular Formula: C16H12O
• Molecular Weight: 220.271
• Mol File: 21236-00-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Furan, 2-[1,1'-biphenyl]-4-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, 2-[1,1'-biphenyl]-4-yl-(21236-00-0)
• EPA Substance Registry System: Furan, 2-[1,1'-biphenyl]-4-yl-(21236-00-0)

Safety Data

• Hazardous Substances Data: 21236-00-0(Hazardous Substances Data)

Upstream product

• 2786-02-9 2-lithiofuran 
• 129236-45-9 [1,1′-biphenyl]-4-yl methanesulfonate 
• 110-00-9 furan 
• 92-67-1 4-phenylalanine 
• 92-52-4 biphenyl 
• 591-50-4 iodobenzene 
• 1449434-91-6 (E)-1-([1,1'-biphenyl]-4-yl)-4-hydroxybut-2-en-1-one 
• 2051-62-9 4'-biphenyl chloride 
• 106-39-8 bromochlorobenzene 
• 591-51-5 phenyllithium 
• 1449482-57-8 1-[3-(toluene-4-sulfonyl)biphenyl-4-yl]naphthalene 
• 584-12-3 2-bromofuran 
• 3315-91-1 4-biphenylylmagnesium bromide 
• 5122-94-1 4-biphenylboronic acid 

Downstream Products

• 1443523-38-3 5,5'-di([1,1'-biphenyl]-4-yl)-2,2'-bifuran 
• 194221-04-0 4-Hydroxy-[1,1';4',1'']terphenyl-2,3-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Photochemical (Hetero-)Arylation of Aryl Sulfonium Salts

The construction of (hetero)biaryls, which are ubiquitous scaffolds among medical substances, functional materials, and agrochemicals, constitutes a key application of cross-coupling methods. However, these usually require multiple synthetic steps. Herein, we report a simple photoinduced and catalyst-free C-H/C-H (hetero)arylation cross-coupling through aryl thianthrenium salts, which are formed site-selectively by direct C-H functionalization. The key to this approach is the UV-light, which can disrupt the C-S bond to form thianthrene radical cations and aryl radicals.

1,2,3-Triazolylidene palladium complex with triazole ligand: Synthesis, characterization and application in Suzuki–Miyaura coupling reaction in water

Palladium complex containing 1,2,3-triazolylidene and a labile triazole moiety has been prepared and characterized. Simple azide alkyne click reaction using three fold excess of dibromoethane afforded 1-(2-bromoethyl)-4-phenyl-1H-1,2,3-triazole. The latter on dehydrobromination yields N-vinyl triazole (Ntzl) which is subsequently used for preparing its triazolium salt. Further, Ntzl–Pd–Ntzl complex was prepared from triazole by simple palladation which underwent a ligand substitution reaction when treated with in situ generated triazolylidene to form Ctzl–Pd–Ntzl type complex. This mixed palladium complex was found to be highly effective in catalyzing Suzuki–Miyaura coupling reaction between aryl halides and aryl boronic acids in water at room temperature with very low catalyst loading.

Synthesis of 2,5-Disubstituted Furans from Sc(OTf)3 Catalyzed Reaction of Aryl Oxiranediesters with γ-Hydroxyenones

A convenient synthesis of 2,5-disubstituted furan was developed by employing donor-acceptor oxiranes in a new reaction with γ-hydroxyenones. Sc(OTf)3 was found to be the best catalyst, and 2,5-disubstituted furans are obtained in moderate to good yields under mild reaction conditions. The scope of the reaction is quite decent, allowing for the synthesis of disubstituted furans having aryl and heteroaromatic groups.