212608-03-2

Basic information

• Product Name: (2S,4S)-4-Acetylsulfanyl-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester
• Synonyms: (2S,4S)-4-Acetylsulfanyl-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester
• CAS NO: 212608-03-2
• Molecular Weight: 474.516
• Mol File: 212608-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-Acetylsulfanyl-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-Acetylsulfanyl-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester(212608-03-2)
• EPA Substance Registry System: (2S,4S)-4-Acetylsulfanyl-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester(212608-03-2)

Safety Data

• Hazardous Substances Data: 212608-03-2(Hazardous Substances Data)

Upstream product

• 4378-70-5 2-aminoethanesulfonamide 

Downstream Products

• 212608-06-5 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-4-methyl-3-[(3S,5S)-1-(4-nitro-benzyloxycarbonyl)-5-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidin-3-ylsulfanyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 212608-04-3 (2S,4S)-4-Mercapto-2-(2-sulfamoyl-ethylcarbamoyl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

Synthesis and biological properties of new 1β-methylcarbapenems

The synthesis and biological activity of the novel series of 1β- methylcarbapenems, 1 and 2 were described. Most compounds displayed high potent antibacterial activity. The best compound in this series, 2a (IH201; R2=NH2) showed an excellent and a broad spectrum as well as high renal DHP- I stability. It also possessed good in vivo efficacy and high safety.