212714-90-4

Basic information

• Product Name: (S)-5-{[(2R,3S,4R,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester
• Synonyms: (S)-5-{[(2R,3S,4R,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester
• CAS NO: 212714-90-4
• Molecular Weight: 780.725
• Mol File: 212714-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-5-{[(2R,3S,4R,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-{[(2R,3S,4R,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester(212714-90-4)
• EPA Substance Registry System: (S)-5-{[(2R,3S,4R,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester(212714-90-4)

Safety Data

• Hazardous Substances Data: 212714-90-4(Hazardous Substances Data)

Upstream product

• 212714-83-5 Diisopropyl-phosphoramidous acid (3aR,4R,6R,6aR)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester methyl ester 
• 110559-89-2 benzyl 4-<(benzyloxycarbonyl)amino>-5-hydroxypentanoate 
• 39946-94-6 4-N-benzoyl-2',3'-O-isopropylidenecytidine 
• 5680-86-4 N-benzyloxycarbonyl-5-O-benzyl-L-glutamic acid 
• 212714-86-8 (S)-5-{[(3aR,4R,6R,6aR)-6-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-methoxy-phosphoryloxy}-4-benzyloxycarbonylamino-pentanoic acid benzyl ester 

Relevant articles and documents

Glutamyl adenylate analogues are inhibitors of glutamyl-tRNA synthetase

Glutamol adenylate 10 was a competitive inhibitor (K(i) = 3 μM) of glutamyl-tRNA synthetase from Escherichia coli. The N6-benzoyl adenine derivative 9 was also an inhibitor (K(i) ~ 60 μM). Replacement of adenine by other bases (purine, cytosine