21273-08-5 Usage
General Description
Phenoxyacetic acid trimethylsilyl ester is a chemical compound that is often used as a reagent in organic synthesis. It is commonly utilized for the protection of carboxylic acids and the preparation of esters and amides. The trimethylsilyl ester group acts as a protecting group, allowing for selective manipulation of functional groups within a molecule. Phenoxyacetic acid trimethylsilyl ester is also used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of various other organic compounds. Additionally, it is known for its ability to enhance the stability and reactivity of certain molecules, making it a valuable tool in chemical research and manufacturing.
Check Digit Verification of cas no
The CAS Registry Mumber 21273-08-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,2,7 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21273-08:
(7*2)+(6*1)+(5*2)+(4*7)+(3*3)+(2*0)+(1*8)=75
75 % 10 = 5
So 21273-08-5 is a valid CAS Registry Number.
21273-08-5Relevant articles and documents
Synthesis of trimethylsilyl carboxylates by HMDS under solvent-free conditions
Jereb, Marjan,Lakner, Janja
, p. 5713 - 5723 (2016/08/23)
A broad set of structurally different carboxylic acids were transformed into their trimethylsilyl esters with HMDS in a practically completely solvent-free process, while a catalytic amount of iodine was required in some cases. The process has several advantages over the known methods: untreated reactants, air atmosphere, mild and neutral conditions, no evolution of hydrogen halide, no need of an additional base, low amount of waste, completely without chromatography, low consumption of energy, and operational simplicity.
Process for preparing acid halides
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, (2008/06/13)
An improved process for preparing trialkylsilyl ester and acid halide derivatives of carboxylic acids is provided along with novel trialkylsilyl ester intermediates of 2-(2-furyl)-2-methoximinoacetic acid.
REACTIONS OF IODOTRIMETHYLSILANE WITH ESTERS OF AROMATIC AND ARALIPHATIC ACIDS
Voronkov, M. G.,Dolmaa, G.,Putilova, G. G.,Dubinskaya, E. I.
, p. 2042 - 2045 (2007/10/02)
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