2129-79-5

Basic information

• Product Name: Phosphinic acid, phenyl(phenylmethyl)-, ethyl ester
• CAS NO: 2129-79-5
• Molecular Formula: C15H17O2P
• Molecular Weight: 260.273
• Mol File: 2129-79-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phosphinic acid, phenyl(phenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic acid, phenyl(phenylmethyl)-, ethyl ester(2129-79-5)
• EPA Substance Registry System: Phosphinic acid, phenyl(phenylmethyl)-, ethyl ester(2129-79-5)

Safety Data

• Hazardous Substances Data: 2129-79-5(Hazardous Substances Data)

Usage

General Description

Phosphinic acid, phenyl(phenylmethyl)-, ethyl ester is a chemical compound with the molecular formula C14H17O2P. It is an ethyl ester of phenyl(phenylmethyl)phosphinic acid, which is a type of organophosphorus compound. This chemical is commonly used as a chemical intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It has also been studied for its potential use as a chiral ligand in asymmetric catalysis. The compound is typically handled and stored in a controlled environment due to its potential hazards and reactivity.

Upstream product

• 10371-42-3 S-(4-methylphenyl) thiobenzoate 
• 172487-18-2 ethyl Phenylphosphinate 
• 103-83-3 N,N'-dimethylbenzylamine 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 7282-98-6 (±)-benzyl(phenyl)phosphinic acid 
• 78-39-7 Triethyl orthoacetate 
• 1638-86-4 diethyl phenylphosphonite 
• 100-44-7 benzyl chloride 

Downstream Products

• 140458-24-8 N--O-trimethylsilylhydroxylamine 
• 188540-15-0 N-hydroxylamine 
• 140458-23-7 α-methylbenzyl(phenyl)phosphinic chloride 
• 66577-36-4 phenyl(1-phenylethyl)phosphinic acid 
• 32395-29-2 benzylphenylphosphinous acid chloride 
• 80863-32-7 benzyl(phenyl)phosphinothioic chloride 
• 7282-98-6 (±)-benzyl(phenyl)phosphinic acid 
• 461003-62-3 phenyl-(1-phenylethyl)phosphinic acid ethyl ester 
• 588-59-0 stilbene 
• 1608-31-7 (cyclohexylidenemethyl)benzene 

Relevant articles and documents

Selective hydrolysis of phosphorus(v) compounds to form organophosphorus monoacids

An azide and transition metal-free method for the synthesis of elusive phosphonic, phosphinic, and phosphoric monoacids has been developed. Inert pentavalent P(v)-compounds (phosphonate, phosphinate, and phosphate) are activated by triflate anhydride (Tf2O)/pyridine system to form a highly reactive phosphoryl pyridinium intermediate that undergoes nucleophilic substitution with H2O to selectively deprotect one alkoxy group and form organophosphorus monoacids.

Palladium-catalyzed phosphorylation of benzyl ammonium triflates with P(O)H compounds

A palladium-catalyzed phosphorylation of benzyl ammonium triflates with P(O)H compounds has been developed. Various benzylphosphorus compounds were produced in good to excellent yields with high functional group tolerance. All the three kinds of hydrogen phosphoryl compounds, i.e. H-phosphonates, H-phosphinates and secondary phosphine oxides, were applicable to this reaction. The successful scale-up experiment and one-pot synthetic operation also well demonstrated its practicality.

Efficient esterification of carboxylic acids and phosphonic acids with trialkyl orthoacetate in ionic liquid

An operationally simple, inexpensive, efficient, and environmentally friendly esterification of various carboxylic acids, phosphonic acids, and phosphinic acids with triethyl orthoacetate or trimethyl orthoacetate under neutral conditions in a typical room temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate, was successfully carried out to provide the corresponding ethyl esters or methyl esters in high yields.