21331-80-6 Usage
Description
(2-DIMETHYLAMINOETHYL)TRIPHENYLPHOSPHONIUM BROMIDE is an almost white to yellow-brown powder that is a polymerizable cationic surfactant. It is known for its ability to intercalate montmorillonite (MMT) and is used in the synthesis of polystyrene-clay nanocomposite materials. Additionally, it is utilized in the synthesis of some analogs of morphine 6-glucuronide through Wittig reactions.
Uses
Used in Polymer and Material Science Industry:
(2-DIMETHYLAMINOETHYL)TRIPHENYLPHOSPHONIUM BROMIDE is used as a polymerizable cationic surfactant for the intercalation of montmorillonite (MMT). This application is crucial in the synthesis of polystyrene-clay nanocomposite materials, which have improved properties such as enhanced mechanical strength, thermal stability, and barrier properties compared to their pure polymer counterparts.
Used in Pharmaceutical Chemistry:
(2-DIMETHYLAMINOETHYL)TRIPHENYLPHOSPHONIUM BROMIDE is used as a key intermediate in the synthesis of some analogs of morphine 6-glucuronide. This application is significant in pharmaceutical chemistry, as these analogs have potential therapeutic uses, particularly in the management of pain and addiction. The use of Wittig reactions in their synthesis allows for the creation of a variety of structurally diverse compounds with potential medicinal properties.
Check Digit Verification of cas no
The CAS Registry Mumber 21331-80-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,3,3 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21331-80:
(7*2)+(6*1)+(5*3)+(4*3)+(3*1)+(2*8)+(1*0)=66
66 % 10 = 6
So 21331-80-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H25NP.BrH/c1-23(2)18-19-24(20-12-6-3-7-13-20,21-14-8-4-9-15-21)22-16-10-5-11-17-22;/h3-17H,18-19H2,1-2H3;1H/q+1;/p-1
21331-80-6Relevant articles and documents
Heterocyclic compound serving as SOS1 inhibitor
-
Paragraph 0166-0168, (2021/08/06)
The invention provides a compound serving as an SOS1 inhibitor, and particularly provides a compound with a structure as shown in a formula (I), or an optical isomer, a pharmaceutically acceptable salt, a prodrug, a deuterated derivative, a hydrate and a solvate of the compound. The compound can be used for treating or preventing diseases or symptoms related to the activity or expression quantity of SOS1.
Synthesis of 2-(N-disubstituted amino)ethyltriphenylphosphonium bromides
Rao, G. Venkateswara,Reddy, G. Chandrasekara
, p. 824 - 826 (2008/04/13)
2-(N-Disubstituted amino)ethyltriphenylphosphonium bromides are prepared in quantitative yields with high purity by reacting secondary amines with 2-methoxyethyltriphenylphosphonium bromide under aqueous conditions. The differential reactivity of this reagent offers advantages for the preparation of aminoethyltriphenylphosphonium bromides possessing nucleophiles such as hydroxy groups.
