213407-13-7

Basic information

• Product Name: 6-(4-chlorophenyl)-4-ureidobutyric acid
• Synonyms: 6-(4-chlorophenyl)-4-ureidobutyric acid
• CAS NO: 213407-13-7
• Molecular Weight: 256.689
• Mol File: 213407-13-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-(4-chlorophenyl)-4-ureidobutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-chlorophenyl)-4-ureidobutyric acid(213407-13-7)
• EPA Substance Registry System: 6-(4-chlorophenyl)-4-ureidobutyric acid(213407-13-7)

Safety Data

• Hazardous Substances Data: 213407-13-7(Hazardous Substances Data)

Upstream product

• 213407-12-6 3-(4-chlorophenyl)-4-ureidobutyric acid methyl ester 
• 1134-47-0 4-amino-3-(4-chlorophenyl)butanoic acid 

Relevant articles and documents

Perhydro-1,3-diazepine-2,4-diones by cyclization of 4-ureidobutyric acids with thionyl chloride: A reinvestigation

The structures of the previously reported aryl-perhydro-1,3-diazepine- 2,4-diones are shown to be pyrrolidinone carboxamide derivatives by nmr spectroscopy.

Synthesis of new 6-(4-chlorophenyl)perhydro-1,3-diazepine-2,4-diones via ureidobutyric acids

Synthesis of new 6-(4-chlorophenyl)perhydro-1,3-diazepine-2,4-diones was accomplished starting from 4-amino-3-(4-chlorophenyl)butyric acid (Baclofen). The chemical pathway involved the cyclisation of various 3-(4-chlorophenyl)- 4-ureidobutyric acids. However, none of the new derivatives retained the anticonvulsant activity of their six-membered ring homologues, belonging to the phenylpyrimidinedione series which we recently described.