213594-73-1

Basic information

• Product Name: 2-bromo-N-(2,6-dimethyl-4-iodophenyl)acetamide
• CAS NO: 213594-73-1
• Molecular Weight: 368.012
• Mol File: 213594-73-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-(2,6-dimethyl-4-iodophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-(2,6-dimethyl-4-iodophenyl)acetamide(213594-73-1)
• EPA Substance Registry System: 2-bromo-N-(2,6-dimethyl-4-iodophenyl)acetamide(213594-73-1)

Safety Data

• Hazardous Substances Data: 213594-73-1(Hazardous Substances Data)

Upstream product

• 87-62-7 2,6-dimethylaniline 
• 22118-09-8 2-bromoacetyl chloride 
• 4102-53-8 4-iodo-2,6-dimethylaniline 

Relevant articles and documents

Preparation and evaluation of some anti-arrhythmic and cardiac inotropic agents as 'cold' analogs of potential myocardial imaging agents

The iodinated anti-arrhythmic analogs of disopyramide (1), procainamide (2) and lidocaine (3) and a new class of imidazolone cardiac inotropic phosphodiesterase inhibitors (4) and (5) (enoximone analogs), were prepared and tested as potential myocardial imaging agents. Compounds 1 and 2 were prepared by direct iodination using iodine monochloride in acetic acid, while 3-5 were prepared from suitable starting materials. The tissue load of the iodinated compounds was determined, in rats, on the basis of their iodine content using adaptation of a recent modification of Sandell and Kolthoff assay. The biodistribution of 125I-iodo derivatives of 2 and 4 were performed in mice. A pharmacokinetic study was performed using 5 to determine the optimal time of imaging post-injection. These compounds have shown significant localization in the heart tissue.