21375-88-2

Basic information

• Product Name: 1-BROMO-2-PHENYLETHYNYL-BENZENE
• Synonyms: 1-BROMO-2-PHENYLETHYNYL-BENZENE;1-(2-Bromophenyl)-2-phenylacetylene;1-(2-Bromophenyl)-2-phenylethyne;1-(Phenylethynyl)-2-bromobenzene;1-Phenyl-2-(2-bromophenyl)ethyne;2-(Phenylethynyl)phenyl bromide;1-bromo-2-(2-phenylethynyl)benzene
• CAS NO: 21375-88-2
• Molecular Formula: C₁₄H₉Br
• Molecular Weight: 258.1332
• Mol File: 21375-88-2.mol
• Article Data: 119

Chemical Properties

• Boiling Point: 155-160 °C(Press: 0.7 Torr)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1-BROMO-2-PHENYLETHYNYL-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-PHENYLETHYNYL-BENZENE(21375-88-2)
• EPA Substance Registry System: 1-BROMO-2-PHENYLETHYNYL-BENZENE(21375-88-2)

Safety Data

• Hazardous Substances Data: 21375-88-2(Hazardous Substances Data)

Usage

Appearance

White to light yellow crystalline solid

Usage

Synthesis of organic compounds and pharmaceuticals

Chemical Groups

Bromine atom, phenyl group, ethynyl group

Versatility

Building block for creating complex molecules

Potential Applications

Materials science, precursor in chemical reactions

Safety Precautions

Potential irritant, hazardous effects if not properly handled or used

Upstream product

• 54737-45-0 (E)-2-bromostilbene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 536-74-3 phenylacetylene 
• 54737-46-1 2,α,α'-tribromo-bibenzyl 
• 100-44-7 benzyl chloride 
• 4706-43-8 1-benzyl-1H-benzotriazole 
• 6630-33-7 ortho-bromobenzaldehyde 
• 591-50-4 iodobenzene 
• 766-46-1 2-bromo-1-ethynylbenzene 
• 159087-45-3 4,4,5,5-tetramethyl-2-phenylethynyl-[1,3,2]dioxaborolane 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 129112-25-0 2-(trifluoromethanesulfonyl)oxy-bromobenzene 
• 583-53-9 2,3-dibromobenzene 
• 10448-07-4 2-bromobenzenediazonium tetrafluoroborate 

Downstream Products

• 58581-32-1 Diphenyl<2-(phenylethinyl)phenyl>phosphan 
• 143192-59-0 1-(phenylethynyl)-2-(trimethylsilylethynyl)benzene 
• 42168-23-0 2-(phenylethynyl)phenyllithium 
• 18434-12-3 1,2-diphenyl-1H-indole 
• 143192-60-3 2-(phenylethynyl)phenylacetylene 
• 383191-43-3 C₄₈H₄₂ 
• 383191-38-6 3-{4-[1-tert-butyl-1-hydroxy-3-(2-phenylethynyl-phenyl)-prop-2-ynyl]-phenyl}-4,4-dimethyl-1-(2-phenylethynyl-phenyl)-pent-1-yn-3-ol 
• 1030023-68-7 chloro[2-(2-phenylethynyl)phenyl](2,4,6-tri-tert-butylphenyl)phosphine 
• 1239896-02-6 2-(tert-butyl)-N-(2-(phenylethynyl)phenyl)aniline 
• 1367458-54-5 2-[2-(phenylethynyl)phenyl]benzo[b]thiophene 
• 1072190-43-2 phenyl-(2-phenyl-indol-1-yl)carbamic acid tert-butyl ester 
• 1264670-28-1 1-(2-phenyl-indol-1-yl)pyrrolidin-2-one 
• 1264670-29-2 2-phenyl-1-pyrrol-1-yl-1H-indole 
• 1264670-30-5 2-phenyl[1,1']biindolyl 

Relevant articles and documents

Incorporation of Palladium Catalyst Inside Cross-Linked Chitosan Hybrid Nanofibers for the Sonogashira Reaction

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Alumina-Mediated π-Activation of Alkynes

The ability to induce powerful atom-economic transformation of alkynes is the key feature of carbophilic π-Lewis acids such as gold- and platinum-based catalysts. The unique catalytic activity of these compounds in electrophilic activations of alkynes is explained through relativistic effects, enabling efficient orbital overlapping with π-systems. For this reason, it is believed that noble metals are indispensable components in the catalysis of such reactions. In this study, we report that thermally activated γ-Al2O3activates enynes, diynes, and arene-ynes in a manner enabling reactions that were typically assigned to the softest π-Lewis acids, while some were known to be triggered exclusively by gold catalysts. We demonstrate the scope of these transformations and suggest a qualitative explanation of this phenomenon based on the Dewar-Chatt-Duncanson model confirmed by density functional theory calculations.

Metal-Free Aminoiodination of Alkynes Under Visible Light Irradiation for the Construction of a Nitrogen-Containing Eight-Membered Ring System

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