21391-29-7Relevant articles and documents
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors
Di Santo, Roberto,Costi, Roberta,Roux, Alessandra,Artico, Marino,Befani, Olivia,Meninno, Tiziana,Agostinelli, Enzo,Palmegiani, Paola,Turini, Paola,Cirilli, Roberto,Ferretti, Rosella,Gallinella, Bruno,La Torre, Francesco
, p. 4220 - 4223 (2005)
Pyrrolylethanoneamines 1-12, 18-23 and related amino alcohols 13-15, 24-27 were synthesized and tested against monoamine oxidases A and B (MAO-A and MAO-B) enzymes. In general, aminoketones 1-12, 18-23 were found to be potent and selective MAO-A inhibitor
