214000-16-5

Basic information

• Product Name: tert-butyl 2-(2-nitrophenylsulfonamido)ethylcarbamate
• Synonyms: tert-butyl 2-(2-nitrophenylsulfonamido)ethylcarbamate
• CAS NO: 214000-16-5
• Molecular Weight: 345.376
• Mol File: 214000-16-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-(2-nitrophenylsulfonamido)ethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2-nitrophenylsulfonamido)ethylcarbamate(214000-16-5)
• EPA Substance Registry System: tert-butyl 2-(2-nitrophenylsulfonamido)ethylcarbamate(214000-16-5)

Safety Data

• Hazardous Substances Data: 214000-16-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 83019-91-4 N-(2-aminoethyl)-2-nitrobenzene-sulfonamide 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 57260-73-8 N-BOC-1,2-diaminoethane 

Downstream Products

• 1429060-11-6 tert-butyl 4-(methylsulfonyl)-3,4-dihydropyrazine-1(2H)-carboxylate 
• 122734-32-1 tert-butyl 2-(methylamino)ethylcarbamate 
• 1429313-27-8 C₁₇H₂₅N₃O₈S 
• 1429313-37-0 C₃₂H₄₃N₇O₇SSi 
• 1429313-36-9 C₂₄H₂₅N₇O₆S 
• 1429313-35-8 C₂₃H₂₃N₇O₆S 
• 1429313-34-7 C₃₃H₃₉N₇O₁₀S 
• 1429313-33-6 C₂₆H₃₄BrN₇O₈S 
• 1429313-32-5 C₁₆H₁₈BrN₇O₄S 
• 1429313-31-4 C₂₄H₂₀BrN₇O₆S 
• 1429313-30-3 C₁₆H₁₇BrN₆O₅S 
• 1429313-29-0 C₁₀H₁₅N₃O₅S 
• 1429313-28-9 C₁₅H₂₃N₃O₇S 
• 862120-81-8 tert-butyl N-{2-[N-(prop-2'-yn-1'-yl)-2-nitrophenylsulfonamido]ethyl}carbamate 

Relevant articles and documents

MACROCYCLIC ACTIVIN-LIKE RECEPTOR KINASE INHIBITORS

The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of Activin-like receptor kinases, more in particular ALK1 and/or ALK2 and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of ALK1-kinase and/or ALK2-kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent.

Chemoselective alkynylation of N-sulfonylamides versus amides and carbamates-Synthesis of tetrahydropyrazines

The chemoselective alkynylation of N-sulfonylamides versus amides and carbamates using TMS-EBX as an alkynylating agent leads to the formation of non-symmetrical tetrahydropyrazines from orthogonally protected diamines. The Royal Society of Chemistry 2013

Concise preparation of 8-trifluoromethyltetrahydro-6H-pyrido [1,2-a] pyrazine-6-one

Methodology to rapidly and efficiently assemble 8-trifluoromethyltetrahydro-6H-pyrido [1,2-a] pyrazine-6-one (11) has been developed and its general applicability has been demonstrated.