214122-05-1

Basic information

• Product Name: (4S)-4-[[(benzyloxy)carbonyl]amino]-3-oxo-5-phenyl-2-triphenylphosphoranylidene-pentanenitrile
• Synonyms: (4S)-4-[[(benzyloxy)carbonyl]amino]-3-oxo-5-phenyl-2-triphenylphosphoranylidene-pentanenitrile
• CAS NO: 214122-05-1
• Molecular Weight: 582.638
• Mol File: 214122-05-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4S)-4-[[(benzyloxy)carbonyl]amino]-3-oxo-5-phenyl-2-triphenylphosphoranylidene-pentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-[[(benzyloxy)carbonyl]amino]-3-oxo-5-phenyl-2-triphenylphosphoranylidene-pentanenitrile(214122-05-1)
• EPA Substance Registry System: (4S)-4-[[(benzyloxy)carbonyl]amino]-3-oxo-5-phenyl-2-triphenylphosphoranylidene-pentanenitrile(214122-05-1)

Safety Data

• Hazardous Substances Data: 214122-05-1(Hazardous Substances Data)

Upstream product

• 1161-13-3 N-Cbz-L-Phe 
• 16640-68-9 cyanomethylene triphenylphosphorane 
• 4336-70-3 (cyanomethyl)triphenylphosphonium chloride 
• 25613-60-9 Nα-carbobenzyloxy-L-phenylalanine N-carboxanhydride 
• 769922-77-2 (S)-benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate 

Downstream Products

• 157683-55-1 (3S)-3-[[(benzyloxy)carbonyl]amino]-2-oxo-4-phenylbutanoic acid methyl ester 
• 1105712-47-7 (2RS)-5-amino-2-benzyl-4-triphenylphosphonio-2,4-dihydropyrrol-3-one bromide 
• 322729-66-8 (2R,3S)-2-hydroxy-4-phenyl-3-[[[3-(phenylazo)benzene]carbonyl]amino]butanoic acid methyl ester 
• 322729-60-2 (2R,3S)-2-hydroxy-4-phenyl-3-[[[4-(phenylazo)benzene]carbonyl]amino]butanoic acid methyl ester 
• 322729-68-0 (3S)-2-oxo-4-phenyl-3-[[[3-(phenylazo)benzene]carbonyl]amino]butanoic acid methyl ester 
• 322729-62-4 (3S)-2-oxo-4-phenyl-3-[[[4-(phenylazo)benzene]carbonyl]amino]butanoic acid methyl ester 
• 126015-22-3 (2R,3S)-3-[[(benzyloxy)carbonyl]amino]-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 126015-23-4 (2S,3S)-3-[[(benzyloxy)carbonyl]amino]-2-hydroxy-4-phenylbutanoic acid methyl ester 

Relevant articles and documents

Triphenylphosphoranylidene substituted heterocycles as versatile intermediates

N-Cbz-(α-aminoacyl)benzotriazoles 5a-e reacted with (stabilized-methylene)triphenylphosphoranes 6 and 13 to give the corresponding esters 7a-e (66-91%) or nitriles 14a-e (63-85%). Deprotection of N-Cbz-γ-amino-β-oxo-α-triphenylphosphoranylidene esters 7a-

Synthesis of cyanoketophosphoranes, precursors of β-amino-α-keto- esters from uncas

Cyanomethylene triphenylphosphoranes of N-protected amino acids were synthesized from the corresponding N-urethane protected or amino acid N- carboxyanhydrides (UNCAs) by reaction with cyanomethyltriphenylphosphonium chloride in good yields. These compoun