21443-48-1 Usage
Description
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-chlorophenyl)methanone] is a type of oxadiazole compound that contains two 4-chlorophenylmethylene groups. It is a white to light yellow crystalline solid and is commonly used in pharmaceutical research as a potential bioactive compound. Its chemical structure and properties make it a promising candidate for further investigation in drug development and medicinal chemistry.
Uses
Used in Pharmaceutical Research:
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-chlorophenyl)methanone] is used as a potential bioactive compound for its anti-inflammatory and antimicrobial properties. Its unique chemical structure allows it to be a promising candidate for further investigation in drug development and medicinal chemistry.
Used in Drug Development:
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-chlorophenyl)methanone] is used as a candidate for the development of new drugs targeting inflammation and microbial infections. Its potential as an anti-inflammatory and antimicrobial agent makes it a valuable asset in the search for novel therapeutic agents.
Used in Medicinal Chemistry:
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-chlorophenyl)methanone] is used as a compound of interest in medicinal chemistry due to its unique chemical structure and potential bioactivity. Researchers are exploring its properties and interactions with biological targets to develop new therapeutic agents and improve existing treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 21443-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,4 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21443-48:
(7*2)+(6*1)+(5*4)+(4*4)+(3*3)+(2*4)+(1*8)=81
81 % 10 = 1
So 21443-48-1 is a valid CAS Registry Number.
21443-48-1Relevant articles and documents
Does electrophilic activation of nitroalkanes in polyphosphoric acid involve formation of nitrile oxides?
Aksenov, Alexander V.,Aksenov, Dmitrii A.,Aksenov, Nicolai A.,Kirilov, Nikita K.,Kurenkov, Igor A.,Nobi, Mezvah A.,Rubin, Michael,Skomorokhov, Anton A.,Sorokina, Elena A.
, p. 35937 - 35945 (2021/12/02)
The mechanistic rationale involving activation of nitroalkanes towards interaction with nucleophilic reagents in the presence of polyphosphoric acid (PPA) was re-evaluated. Could nitrile oxide moieties be formed during this process? This experiment demonstrates that at least in some cases this could happen, as generated nitrile oxides were successfully intercepted as adducts of [3 + 2] cycloadditions. This journal is
Synthesis of Furoxans and Isoxazoles via Divergent [2 + 1 + 1 + 1] Annulations of Sulfoxonium Ylides and tBuONO
Tang, Zhonghe,Zhou, Yao,Song, Qiuling
, p. 5273 - 5276 (2019/09/03)
We have presented a simple and new method for the divergent assembly of furoxans and isoxazoles in which the [2 + 1 + 1 + 1] annulation reaction of sulfoxonium ylides is reported for the first time. When the reaction was performed using tBuONO
10-Hydroxy-7-arylindeno[1,2-b]-1,2,5-oxadiazolo[3,4-d]pyridines and 7- aryl-10-oxoindeno[1,2-b]-1,2,5-oxadiazolo[3,4-d]pyridines-synthesis, spectra, and polymorphism
Mataka, Shuntaro,Gorohmaru, Hideki,Thiemann, Thies,Sawada, Tsuyoshi,Takahashi, Kazufumi,Tori-i, Akiyoshi
, p. 895 - 902 (2007/10/03)
The novel dyes 7-aryl- 10-oxoindeno[1,2-b]-1,2,5-oxadiazolo[3,4-d]- pyridines (4) and 7-aryl-10-hydroxyindeno[1,2-b]-1,2,5-oxadiazolo[3,4-d]- pyridines (5) have been prepared from acetophenone derivatives. While compounds (4) exhibit a dark red color, the
