214492-04-3

Basic information

• Product Name: (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one
• Synonyms: (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one
• CAS NO: 214492-04-3
• Molecular Weight: 261.321
• Mol File: 214492-04-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one(214492-04-3)
• EPA Substance Registry System: (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one(214492-04-3)

Safety Data

• Hazardous Substances Data: 214492-04-3(Hazardous Substances Data)

Upstream product

• 103422-95-3 (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one 
• 74-88-4 methyl iodide 
• 25145-43-1 (2S)-2-phenylpropionyl chloride 
• 95530-58-8 (R)-4-isopropyloxazolidin-2-one 

Downstream Products

• 37778-99-7 (S)-2-phenyl-1-propanol 

Relevant articles and documents

Conformational control in the SuperQuat chiral auxiliary 5,5-dimethyl-4-iso-propyloxazolidin-2-one induces the iso-propyl group to mimic a tert-butyl group

1H NMR nOe spectroscopic studies reveal that conformational control in the enolates of N-acyl-5,5-dimethyl-4-iso-propyloxazolidin-2-ones ensures that the stereodirecting effect of its 4-iso-propyl-5,5-dimethyl functional group affords superior levels of facial selectivity normally associated with enolates derived from N-acyl-4-tert-butylox-azolidin-2-ones.

Probing the resolution of 2-phenylpropanoyl chloride using quasi-enantiomeric Evans' oxazolidinones

The parallel kinetic resolution of 2-phenylpropanoyl chloride using quasi-enantiomeric oxazolidinones is discussed. The levels of diastereoselectivity were found to be dependent on the presence of an additional (quasi)-enantiomeric oxazolidinone and its s