2146-61-4

Basic information

• Product Name: 3-METHOXYPHENETHYL BROMIDE
• Synonyms: 1-(2-Bromoethyl)-3-methoxybenzene;Anisole, m-(2-bromoethyl)-;Benzene, 1-(2-bromoethyl)-3-methoxy-;m-Methoxyphenethyl bromide;m-Methoxyphenylethyl bromide;3-Methoxyphenylethylbromide;3-Methoxyphenethyl broMide 97%
• CAS NO: 2146-61-4
• Molecular Formula: C₉H₁₁BrO
• Molecular Weight: 215.08704
• Mol File: 2146-61-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 172-209 °C (DSC)(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.3708 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0298mmHg at 25°C
• Refractive Index: n20/D 1.5593(lit.)
• CAS DataBase Reference: 3-METHOXYPHENETHYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXYPHENETHYL BROMIDE(2146-61-4)
• EPA Substance Registry System: 3-METHOXYPHENETHYL BROMIDE(2146-61-4)

Safety Data

• Hazard Codes: C
• Statements: 22-34-52/53
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 2
• Hazardous Substances Data: 2146-61-4(Hazardous Substances Data)

Usage

General Description

3-Methoxyphenethyl bromide, also known as 3-methoxyphenethyl bromide, is a chemical compound that consists of a phenethyl group with a methoxy substituent and a bromine atom. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. This chemical is reactive and can undergo various chemical reactions such as nucleophilic substitution and oxidation. It is important to handle 3-methoxyphenethyl bromide with care and use appropriate safety measures due to its potential hazards.

InChI:InChI=1/C9H11BrO/c1-11-9-4-2-3-8(7-9)5-6-10/h2-4,7H,5-6H2,1H3

Upstream product

• 35553-92-5 ETHYL 3-METHOXYPHENYLACETATE 
• 18927-05-4 methyl (3-methoxyphenyl)acetate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 1798-09-0 m-methoxyphenylacetic acid 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 

Downstream Products

• 198630-95-4 2-(2-Bromo-5-methoxyphenyl)ethyl bromide 
• 855897-15-3 2-(3-methoxy-phenethyl)-3-oxo-heptanedioic acid diethyl ester 
• 111171-90-5 (3-methoxy-phenethyl)-malonic acid diethyl ester 
• 114275-95-5 1-(3-methoxy-phenethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 90350-30-4 3-(2-bromo-ethyl)-4-chloro-anisole 
• 93457-54-6 2-(m-Anisyl)ethylhydrazin 
• 6321-53-5 2-[2-(3-methoxyphenyl)ethyl]cyclohexane-1,3-dione 
• 40463-20-5 1-methoxy-3-(pent-4-en-1-yl)benzene 
• 52059-58-2 N-Methyl-β-(m-methoxy-phenyl)-β'-phenyl-diaethylamin 
• 78661-18-4 2-Methoxycarbonyl-5,5-dimethyl-2-(m-methoxyphenyl)-cyclohexanone 
• 74670-02-3 Methyl 2-<β-(m-methoxyphenyl)ethyl>-cyclopentan-1-one-2,3-dicarboxylate 
• 135215-63-3 (E)-ethyl 2-<2-(3-methoxyphenyl)ethyl>-6-methyl-2-oxo-6,10-undecadienoate 
• 135677-59-7 (E)-2-[2-(3-Methoxy-phenyl)-ethyl]-6-methyl-3-oxo-dodeca-6,11-dienoic acid ethyl ester 
• 73593-68-7 (+)-(1S,7aS)-1-tert-Butoxy-1,2,3,6,7,7a-hexahydro-4-<2-(3-methoxyphenyl)ethyl>-7a-methyl-5H-inden-5-on 

Relevant articles and documents

The Tricyclooctanone Approach to the Total Synthesis of Steroids. The Cyclization of the A-CD Unit

The first steps of a novel approach to the total synthesis of 9,11-dehydroestrone via tricyclo2,8>octan-3-one (2) are described.One route involves a tandem-type transformation of the key intermediate 3 (A-CD unit) consisting of cyclopro

A concise approach to anthraquinone-xanthone heterodimers

A synthetic approach to anthraquinone-xanthone heterodimers is described. The route to the pentacyclic core features an efficient assembly of a benzocycloheptenone via a new intramolecular oxidative arylation of an enol ether and a Hauser-Kraus annulation-aldol reaction sequence to access the characteristic bicyclo[3.2.2]nonene motif. Acremoxanthone A is synthesized in 10 steps from commercially available material to demonstrate the application of this approach.

Synthesis and biological activities of the marine bryozoan alkaloids convolutamines A, C and F, and lutamides A and C

Synthesis of convolutamines and lutamides, new 2,4,6-tribromo-3-methoxyphenethylamine alkaloids isolated from Floridian marine bryozoan Amathia convoluta, was accomplished by a sequence of reactions starting from 3-hydroxyphenethylamines. Cytotoxities of the synthetic lutamides, convolutamines and their de-O-methyl derivatives were examined using drug-sensitive and -resistant P388 as well as KB cell lines. The bioassay suggests that the 2,4,6-tribromo-3-methoxyphenethylamine is an indispensable unit for detection of the activities. Additionally, a reversal of drug resistance by those alkaloids is recognized. Copyright (C) 2000 Elsevier Science Ltd.