21464-41-5

Basic information

• Product Name: α,α-Diphenyl-1,2-benzoldimethanol
• Synonyms: α,α-Diphenyl-1,2-benzoldimethanol
• CAS NO: 21464-41-5
• Molecular Weight: 290.362
• Mol File: 21464-41-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: α,α-Diphenyl-1,2-benzoldimethanol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-Diphenyl-1,2-benzoldimethanol(21464-41-5)
• EPA Substance Registry System: α,α-Diphenyl-1,2-benzoldimethanol(21464-41-5)

Safety Data

• Hazardous Substances Data: 21464-41-5(Hazardous Substances Data)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 591-51-5 phenyllithium 
• 100-58-3 phenylmagnesium bromide 
• 100-51-6 benzyl alcohol 
• 119-61-9 benzophenone 
• 596-29-2 3,3-diphenyl-2-benzofuran-1(3H)-one 

Downstream Products

• 602-55-1 9-phenylanthracene 
• 7449-50-5 1,1-diphenyl-1,3-dihydrobenzofuran 
• 151153-52-5 1,1-diphenyl-1,3-dihydrobenzothiophene 
• 596-29-2 3,3-diphenyl-2-benzofuran-1(3H)-one 
• 160375-76-8 N⁶-cyclohexyl-5'-O-<(2-t-butyldiphenylsilyloxymethylphenyl)diphenylmethyl>adenosine 
• 160375-72-4 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethyl chloride 
• 6624-01-7 2-Hydroxymethyl-triphenylmethan 
• 160375-88-2 1-<2-(t-butyldiphenylsilyloxymethyl)phenyl>-1,1-diphenylmethanol 

Relevant articles and documents

Electron-transfer-induced reductive cleavage of phthalans: Reactivity and synthetic applications

The behavior of phthalan (1a) was investigated under conditions of electron transfer from alkali metals in aprotic solvents. Reaction with lithium in the presence of a catalytic amount of naphthalene in THF led to the reductive cleavage of an arylmethyl carbon-oxygen bond, with formation of a stable dilithium compound. Trapping of this intermediate with several electrophiles (alkyl halides, carbonyl derivatives, CO2) was successful. The extension of this procedure to several substituted phthalans (1b-i) was investigated, and the regiochemistry as well as the synthetic usefulness of these reactions are discussed.

Direct ortho-Metalation of Benzyl Alcohols. A Novel Method of Preparing ortho-Substituted Benzyl Alcohols

Benzyl alcohol and other phenylcarbinols (8a - 11a), including α-tetralol (12a), are doubly deprotonated by excess n-butyllithium/TMEDA in pentane to give lithium ortho-lithioalkoxides (2, 8b - 12b).Alkylations (-> 3a - d, table 1), reactions with heteroelectrophiles (-> 3e - k, table 2) and with carbonyl compounds (-> 6, 13 - 17, tables 3 and 4), as well as subsequent reactions of the primary adducts (-> phthalanes 7, table 3) furnish a large variety of ortho-substituted benzyl alcohol derivatives.The scope and limitations of the dilithioorganyls (sections B and C), their mode of formation (section A), and attempts to doubly metalate 2-phenylethanol are discussed.

Findings on 2,3-benzoxazine. VII. (1)-4-phenyl-1H-3,4-dihydro-2,3-benzozazine and derivatives

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