21472-93-5 Usage
Chemical structure
1,3-Diethylthymine is a chemical compound that is structurally related to thymine, a nucleotide base found in DNA, with two ethyl groups attached to the 1 and 3 positions.
Composition
It is composed of a thymine molecule with two ethyl groups attached.
Usage in research
1,3-Diethylthymine is mainly used in scientific research as a probe to study DNA and RNA structures and functions.
Application in organic synthesis
It is employed as a building block in organic synthesis, particularly in the production of modified nucleic acids and related compounds.
Potential pharmaceutical applications
1,3-diethylthymine has potential applications in the development of pharmaceuticals targeting DNA and RNA-based diseases.
Unique properties
Due to its molecular structure and reactivity, 1,3-diethylthymine has unique properties that make it a valuable tool in various biochemical and pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 21472-93-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,7 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21472-93:
(7*2)+(6*1)+(5*4)+(4*7)+(3*2)+(2*9)+(1*3)=95
95 % 10 = 5
So 21472-93-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N2O2/c1-4-10-6-7(3)8(12)11(5-2)9(10)13/h6H,4-5H2,1-3H3
21472-93-5Relevant articles and documents
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Tanabe et al.
, p. 3021,3022 (1977)
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HSAB-driven chemoselective N1-alkylation of pyrimidine bases and their 4-methoxy- or 4-acetylamino-derivatives
Gambacorta, Augusto,Tofani, Daniela,Loreto, Maria Antonietta,Gasperi, Tecla,Bernini, Roberta
, p. 6848 - 6854 (2007/10/03)
The lithium salts of the conjugated bases of 4-methoxy- and 4-acetylamino-2(1H)-pyrimidinones 1-3 undergo highly chemoselective N1-methylation or ethylation when treated with methyl- or ethylsulfate (hard electrophiles) in dry dioxane, while the use of DMF as solvent results in competitive O2-alkylation. Potassium salts of the same bases in DMF undergo prevalent O2-attack. Under the same conditions, a similar but less chemoselective behaviour is observed in alkylation of thymine and uracil, where some N3-attack occurs. This can be rationalised in terms of the HSAB principle.
