215057-28-6

Basic information

• Product Name: 2,3-Dihydro-1-benzofuran-5-propanoic acid
• Synonyms: 2,3-dihydrobenzofuran-5-propanoic acid;2,3-Dihydrobenzofuran-5-Propionic Acid;2,3-Dihydro-1-benzofuran-5-propanoic acid;2,3-dihydro-5-Benzofuranpropanoic acid;2,3-Dihydro-1-benzof;3-Dihydrobenzofuran-5-propanoic acid;5-(2-Carboxyethyl)-2,3-dihydro-1-benzofuran;5-Benzofuranpropanoic acid, 2,3-dihydro-
• CAS NO: 215057-28-6
• Molecular Formula: C11H12O3
• Molecular Weight: 192.21
• EINECS: 1533716-785-6
• Product Categories: Fluorobenzene;Furans
• Mol File: 215057-28-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 95-97°C
• Boiling Point: 355.2 °C at 760 mmHg
• Flash Point: 142.1 °C
• Appearance: /
• Density: 1.252 g/cm³
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: 2-8°C
• PKA: 4.61±0.10(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-1-benzofuran-5-propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-1-benzofuran-5-propanoic acid(215057-28-6)
• EPA Substance Registry System: 2,3-Dihydro-1-benzofuran-5-propanoic acid(215057-28-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 215057-28-6(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1-benzofuran-5-propanoic acid is a chemical compound that falls under the category of organooxygen compounds, specifically benzo-furans. Benzofurans are heterocyclic compounds that combine fused benzene and furan rings. This particular compound has a molecular formula of C12H14O3. It doesn't appear to be widely known or studied, hence, specific information about its properties, uses or safety measures may not be currently available. Each industrial use would have different safety parameters and it is also important to mention that any handling of this chemical should follow appropriate safety protocols.

InChI:InChI=1/C11H12O3/c12-11(13)4-2-8-1-3-10-9(7-8)5-6-14-10/h1,3,7H,2,4-6H2,(H,12,13)

Upstream product

• 198707-57-2 3-(2,3-dihydro-1-benzofuran-5-yl)prop-2-enoic acid 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 496-16-2 2.3-dihydrobenzofuran 
• 203505-84-4 3-(2,3-dihydro-1-benzofuran-5-yl)-2-propenoic acid 

Downstream Products

• 196597-76-9 ethyl 3-(6,7-dibromo-2,3-dihydrobenzofuran-5-yl) propionic acid 
• 196597-26-9 ramelteon 
• 196597-77-0 4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one 
• 196597-78-1 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one 

Relevant articles and documents

NOVEL COMPOUNDS AND USES

The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and R2 is a cyclic group substituted at the α-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the dual action of NLRP3 inhibition and the stimulation of insulin secretion.

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES

The present invention provides processes and intermediates for the synthesis of ramelteon.