215095-77-5 Usage
General Description
The chemical (9,16b)-9,11-Epoxy-16,17,21-trihydroxypregna-1,4-diene-3,20-dione, also known as triamcinolone, is a synthetic corticosteroid used for its anti-inflammatory and immunosuppressive properties. It is commonly used to treat various skin conditions, allergies, and inflammatory disorders. Triamcinolone works by reducing inflammation, swelling, and redness, and is available in various forms including creams, ointments, and injections. However, it is important to use this medication under the guidance of a healthcare professional, as prolonged or excessive use can lead to adverse effects such as thinning of the skin, acne, and increased risk of infection.
Check Digit Verification of cas no
The CAS Registry Mumber 215095-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,0,9 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 215095-77:
(8*2)+(7*1)+(6*5)+(5*0)+(4*9)+(3*5)+(2*7)+(1*7)=125
125 % 10 = 5
So 215095-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H26O6/c1-18-6-5-12(23)7-11(18)3-4-13-14-8-15(24)20(26,16(25)10-22)19(14,2)9-17-21(13,18)27-17/h5-7,13-15,17,22,24,26H,3-4,8-10H2,1-2H3/t13-,14-,15+,17?,18-,19-,20-,21?/m0/s1
215095-77-5Relevant articles and documents
Preparation process of triamcinolone acetonide
-
Paragraph 0008, (2017/07/21)
The invention relates to a preparation process of triamcinolone acetonide. The triamcinolone acetonide is prepared by taking an intermediate III as a raw material. The preparation process comprises the following steps of: by taking a hydrofluoric acid-acetone mixed solvent as a solvent, slowly adding the intermediate III in a temperature range of 40 DEG C below zero to 30 DEG C below zero; after adding the raw material, performing a reaction for 4-8 hours; returning the temperature to 5 DEG C below zero to zero DEG C, and continuously performing a reaction for 10-30 min; after reaction, slowly adding the reaction liquid into a potassium carbonate solution; adjusting the PH value to 7.0-7.5; filtering and discharging the material; and drying the same to obtain triamcinolone acetonide. The preparation process shortens the production period, prevents use of a lot of high-matching acetone and is more environmentally friendly.
