21545-31-3

Basic information

• Product Name: 2,3-Dihydro-1,4-naphthoquinone
• Synonyms: 2,3-Dihydro-1,4-naphthoquinone
• CAS NO: 21545-31-3
• Molecular Formula: C₁₀H₈O₂
• Molecular Weight: 160.16932
• Mol File: 21545-31-3.mol
• Article Data: 27

Chemical Properties

• Melting Point: 98 °C
• Boiling Point: 320.0±22.0 °C(Predicted)
• Appearance: /
• Density: 1.239±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-1,4-naphthoquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-1,4-naphthoquinone(21545-31-3)
• EPA Substance Registry System: 2,3-Dihydro-1,4-naphthoquinone(21545-31-3)

Safety Data

• Hazardous Substances Data: 21545-31-3(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1,4-naphthoquinone, also known as menadione, is a synthetic compound that is structurally similar to vitamin K. It is a yellow crystalline powder that is commonly used in the production of vitamin K supplements and as a precursor to other forms of vitamin K. Menadione is also used as an intermediate in the synthesis of pharmaceuticals and as a chemical reagent in laboratory experiments. However, despite its beneficial uses, menadione has been reported to have toxic effects on the liver and can potentially cause hemolytic anemia in high doses, leading to its limited use in food and pharmaceutical applications.

Upstream product

• 6295-28-9 5,8-dihydronaphthalene-1,4-dione 
• 119-64-2 tetralin 
• 75-91-2 tert.-butylhydroperoxide 
• 529-33-9 1,2,3,4-Tetrahydro-1-naphthol 
• 3090-45-7 5,8-dihydro-1,4-naphthalenediol 
• 130-15-4 [1,4]naphthoquinone 
• 87051-06-7 1,8-Dimethoxy-9,10-dioxa-tricyclo[6.2.2.0^2,7]dodeca-2⁽⁷⁾,3,5,11-tetraene 
• 75-07-0 acetaldehyde 

Downstream Products

• 136229-46-4 2-(2-hydroxyphenyl)anthraquinone 
• 796-30-5 1,4-diphenylnaphthalene 
• 571-58-4 1,4-dimethylnaphthalene 
• 5697-00-7 1,4-diacetoxynaphthalene 

Relevant articles and documents

Chromium-promoted benzylic oxidations by tert-butyl hydroperoxide: A new catalyst and a comparison of the different procedures

Homogeneous data from literature reports concerning chromium-induced benzylic oxidations by tert-butyl hydroperoxide and from an efficient system using bistriphenylsilyl chromate as catalyst are presented.

A Copper-Containing Polyoxometalate-Based Metal-Organic Framework as an Efficient Catalyst for Selective Catalytic Oxidation of Alkylbenzenes

A copper-containing polyoxometalate-based metal-organic framework (POMOF), CuI12Cl2(trz)8[HPW12O40] (HENU-7, HENU = Henan University; trz = 1,2,4-triazole), has been successfully synthesized and well-characterized. In addition, the excellent catalytic ability of HENU-7 has been proved by the selective oxidation of diphenylmethane. Under the optimal conditions, the diphenylmethane conversion obtained over HENU-7 is 96%, while the selectivity to benzophenone is 99%, which outperforms most noble-metal-free POM-based catalysts. Moreover, HENU-7 is stable to reuse for five runs without an obvious loss in activity and also can catalyze the oxidation of different benzylic C-H with satisfactory conversions and selectivities, which implied the significant catalytic activity and recyclability.

Oxyfunctionalization of Alkanes Based on a Tricobalt(II)-Substituted Dawson-Type Rhenium Carbonyl Derivative as Catalyst

POM-supported metal carbonyl derivatives (PMCDs) represent a family of tremendous potential catalysts owing to their peculiar physical and chemical properties. Yet low-valence transition metal-substituted Dawson-type PMCD catalysts are uncommon. Hence, we synthesized a tricobalt-substituted PMCDs by conventional aqueous solution method, [Na(H2O)5](NH4)7[P2W15O56Co3(H2O)3(OH)3Re(CO)3]·13H2O (1), and characterized by single crystal X-ray diffraction crystallography, IR, and thermogravimetric analyses (TGA), etc. The obtained compound 1 was employed as a catalyst for the oxidation of diphenylmethane (DPM) to benzophenone, giving 96.8percent yield in the presence of tert-butyl hydroperoxide (TBHP) and pyridine. The control experiments indicate that Co metal ion plays an important role in the catalytic reactions. As a side note, the electrospray ionization mass spectrometry (ESI-MS) and UV spectroscopy showed that 1 can retain its integrity in solution, and magnetic measurements indicated that 1 exhibited a weaker ferromagnetic interaction at low temperature.