215453-29-5

Basic information

• Product Name: N-[6-(hydroxymethyl)-1-isoquinolinyl]benzamide
• Synonyms: N-[6-(hydroxymethyl)-1-isoquinolinyl]benzamide
• CAS NO: 215453-29-5
• Molecular Weight: 278.31
• Mol File: 215453-29-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[6-(hydroxymethyl)-1-isoquinolinyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[6-(hydroxymethyl)-1-isoquinolinyl]benzamide(215453-29-5)
• EPA Substance Registry System: N-[6-(hydroxymethyl)-1-isoquinolinyl]benzamide(215453-29-5)

Safety Data

• Hazardous Substances Data: 215453-29-5(Hazardous Substances Data)

Upstream product

• 215453-25-1 6-Bromo-1-phenoxyisoquinoline 
• 215453-26-2 (6-bromoisoquinolin-1-yl)amine 
• 205055-63-6 6-bromo-1-chloroisoquinoline 
• 215453-28-4 N-(6-formyl-1-isoquinolinyl)benzamide 
• 34784-05-9 6-bromo-isoquinoline 

Downstream Products

• 215453-30-8 [[-(benzoylamino)-6-isoquinolinyl]methyl][[(1,1-dimethylethoxy)carbonyl]amino]propane-dioic acid diethyl ester 
• 223770-00-1 rac-6-(1-aminoisoquinolinyl)alanine 

Relevant articles and documents

1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors

Replacement of the highly basic benzamidine moiety of NAPAP by the moderately basic 1-aminoisoquinoline moiety resulted in thrombin inhibitors with improved selectivity towards trypsin and enhanced Caco-2 cell permeability.