215655-76-8Relevant articles and documents
Preparation method and production device of clacyfos
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Paragraph 0066; 0067; 0068; 0069; 0070; 0071; 0072, (2017/01/02)
The invention discloses a production method of clacyfos. After hydroxyphosphonate and a first organic solvent are mixed, an acid-binding agent and a catalyst are sequentially added and stirred, the temperature is adjusted to be -50-70 DEG C, 2,4-dichlorbenzoxyacetyl chloride is added dropwise into reaction liquid, the temperature is controlled to be -50-70 DEG C, and stirring is conducted for 0.5-6 h; after reaction, water is added, stirring is conducted for 0.5-1 h, then the mixture stands still for 0.5-1 h, and an aqueous phase and an organic phase are separated; the organic phase is subjected to desolvation and spinning drying, and clacyfos is obtained. The production method is high in yield, the product content is high, the solvent can be recycled, and environmental friendliness is achieved. The invention further discloses a production device of clacyfos. The production device comprises a metering tank (1), a dropwise adding tank (2), a synthesis kettle (3), a washing kettle (4), a distillation kettle (5), a solvent receiving tank (6), a vacuumizing pipeline (B), a freezing pipeline and a steam heating device. The production device can achieve full-automatic integrated continuous production, the whole device is fully sealed, air pollution does not exist, the wastewater amount is small, and environment protection is benefited.
Synthesis and herbicidal activities of lithium or potassium hydrogen 1-(substituted phenoxyacetoxy)alkylphosphonates
Peng, Hao,Long, Qingwu,Deng, Xiaoyan,He, Hongwu
, p. 1868 - 1874 (2013/11/06)
A series of lithium or potassium hydrogen 1-(substituted phenoxyacetoxy)alkylphosphonates were designed and synthesized. All the title compounds were identified by IR, 1H NMR, and 31P NMR, some of them were further analyzed by MS and elemental analyses. The test for herbicidal activity indicated that most of the phosphonates (8) possessed excellent postemergence herbicidal activities against broadleaf weeds. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
Synthesis and herbicidal activities of methyl-1-(2,4- dichlorophenoxyacetoxy)alkylphosphonate monosalts
He, Hong Wu,Wang, Tao,Yuan, Jun Lin
, p. 2608 - 2613 (2007/10/03)
A series of 1-(2,4-dichlorophenoxyacetoxy)alkylphosphonic acid dimethyl esters 5 and its corresponding phosphonate monosalts 6 were synthesized as potential herbicide. The phosphonate monosalts can be prepared from 1-(2,4-dichlorophenoxyacetoxy)alkylphosphonic acid dimethyl esters 5, which were synthesized by the condensation of O,O-dimethyl-1-hydroxyalkylphosphonates with dichlorophenoxyacetic chloride. This method provides a simple and efficient procedure for the synthesis of phosphonate derivatives containing sensitive groups to acid, base or water such as carboxylate ester bond; and the herbicidal activity of title compounds was evaluated in a set of experiments in greenhouse. Most of the compounds exhibited notable herbicidal activity.
