215675-45-9 Usage
Molecular Structure
1H-Imidazole, 1-ethyl-4,5-dimethyl-, 3-oxide(9CI) consists of an imidazole ring with an ethyl group at position 1 and methyl groups at positions 4 and 5, with an oxygen atom attached to position 3 of the imidazole ring.
Chemical Class
The compound is an imidazole derivative, which is a heterocyclic aromatic organic compound.
Applications
The compound is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is also used in various biochemical and organic chemical research.
Biological and Pharmacological Activities
As an imidazole derivative, the compound has potential biological and pharmacological activities, making it an important compound for further study and development.
Physical Properties
The specific physical properties of 1H-Imidazole, 1-ethyl-4,5-dimethyl-, 3-oxide(9CI) are not provided in the material.
Stability
The stability of 1H-Imidazole, 1-ethyl-4,5-dimethyl-, 3-oxide(9CI) is not provided in the material.
Safety Profile
The safety profile of 1H-Imidazole, 1-ethyl-4,5-dimethyl-, 3-oxide(9CI) is not provided in the material. However, as with all chemicals, appropriate safety precautions should be taken when handling this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 215675-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,6,7 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 215675-45:
(8*2)+(7*1)+(6*5)+(5*6)+(4*7)+(3*5)+(2*4)+(1*5)=139
139 % 10 = 9
So 215675-45-9 is a valid CAS Registry Number.
215675-45-9Relevant articles and documents
First Examples of Reactions of Azole N-Oxides with Thioketones: A Novel Type of Sulfur-Transfer Reaction
Mloston, Grzegorz,Gendek, Tomasz,Heimgartner, Heinz
, p. 1585 - 1595 (2007/10/03)
The reactions of 1,4,5-trisubstituted imidazole 3-oxides 1a-k with cyclobutanethiones 5a,b in CHCl3 at room temperature give imidazole-2(3H)-thiones 9a-k in high yield. The second product formed in this reaction is 2,2,4,4-tetramethylcyclobutane-1,3-dione (6a; Scheme 2). Similar reactions occur with 1 and adamantanethione (5c) as thiocarbonyl compound, as well as with 1,2,4-triazole-4-oxide derivative 10 and 5a (Scheme 3). A reaction mechanism by a two-step formation of the formal cycloadduct of type 7 via zwitterion 16 is proposed in Scheme 5. Spontaneous decomposition of 7 yields the products of this novel sulfur-transfer reaction. The starting imidazole 3-oxides are conveniently prepared by heating a mixture of 1,3,5-trisubstituted hexahydro-1,3,5-triazines 3 and α-(hydroxyimino) ketones 2 in EtOH (cf. Scheme 1). As demonstrated in the case of 9d, a 'one-pot' procedure allows the preparation of 9 without isolation of the imidazole 3-oxides 1. The reaction of 1c with thioketene 12 leads to a mixture of four products (Scheme 4). The minor products, 9c and the ketene 15, result from an analogous sulfur-transfer reaction (Path a in Scheme 5), whereas the parent imidazole 14 and thiiranone 13 are the products of an oxygen-transfer reaction (Path b in Scheme 5).
