21582-51-4

Basic information

• Product Name: 2-methylthieno[2,3-d]pyrimidin-4(3H)-one
• Synonyms: 2-methylthieno[2,3-d]pyrimidin-4(3H)-one;2-methylthieno[2,3-d]pyrimidin-4-ol;2-methylthieno[3,2-d]pyrimidin-4-ol;2-methylthieno[2,3-d]pyrimidin-4(3H)-one(SALTDATA: FREE);2-Methyl-3H-thieno[2,3-d]pyrimidin-4-one;2-Methyl-3,4-dihydro-4-oxothieno[2,3-d]pyrimidine
• CAS NO: 21582-51-4
• Molecular Formula: C7H6N2OS
• Molecular Weight: 166.20034
• Mol File: 21582-51-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 204-206℃
• Appearance: /
• Density: 1.53
• Refractive Index: 1.752
• CAS DataBase Reference: 2-methylthieno[2,3-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylthieno[2,3-d]pyrimidin-4(3H)-one(21582-51-4)
• EPA Substance Registry System: 2-methylthieno[2,3-d]pyrimidin-4(3H)-one(21582-51-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 21582-51-4(Hazardous Substances Data)

Usage

General Description

"2-methylthieno[2,3-d]pyrimidin-4(3H)-one" is a chemical compound with a molecular formula C7H6N2OS. It belongs to the class of thienopyrimidine compounds and is characterized by its unique ring structure. 2-methylthieno[2,3-d]pyrimidin-4(3H)-one has potential applications in the field of medicinal chemistry and pharmaceuticals, as it can exhibit various biological activities and properties. Further research and studies are being conducted to explore the potential therapeutic uses and applications of this chemical in the pharmaceutical industry.

InChI:InChI=1/C7H6N2OS/c1-4-8-6(10)5-2-3-11-7(5)9-4/h2-3H,1H3,(H,8,9,10)

Upstream product

• 55654-14-3 2-acetylaminothiophene-3-carboxylic acid amide 
• 55654-18-7 N-(3-cyanothiophen-2-yl)acetamide 
• 4651-82-5 2-amino-3-cyanothiophene 
• 4651-81-4 Methyl 2-aminothiophene-3-carboxylate 
• 75-05-8 acetonitrile 
• 31891-06-2 ethyl 2-aminothiophene-3-carboxylate 
• 14080-51-4 2-aminothiophene-3-carboxamide 
• 75-36-5 acetyl chloride 

Downstream Products

• 56843-79-9 4-chloro-2-methylthieno[2,3-d]pyrimidine 
• 56844-01-0 2-methyl-thieno[2,3-d]pyrimidine 

Relevant articles and documents

THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS

The present disclosure provides compounds, methods, and compositions which may be used to treat tuberculosis. In some embodiments, these compounds and compositions have a bactericidal property against Mycobacterium tuberculosis (Mtb). Methods of employing such agents are also provided.

MONOCYCLIC, THIENO, PYRIDO, AND PYRROLO PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE OF THE SAME

The present invention provides monocyclic, thieno, pyrido and pyrrolo pyrimidine compounds. Pharmaceutical compositions comprising one or more of these compounds and optionally comprising a pharmaceutically acceptable salt or hydrate of one or more of the compounds are provided. Preferably, these pharmaceutical compositions further comprise at least one pharmaceutically acceptable carrier. Methods of treating a patient having cancer are provided wherein a therapeutically effective amount of one or more of these compounds or pharmaceutical compositions are administered to the patient.

Antiviral Activity of Novel Bicyclic Heterocycles

The present invention relates to compound of Formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1 or as described in detail in the description of the invention, and to the use of said compounds to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with RNA-viruses belonging to the family of the Retroviridae, the family of the Flaviviridae and the family of the Picornaviridae and more preferably infections with Human Immunodeficiency Virus 1 (HIV1), Human Immunodeficiency Virus 2 (HIV2), Hepatitis C virus (HCV), Dengue virus, and enteroviruses like Coxsackievirus, Rhinovirus and Poliovirus. The present invention also relates to pharmaceutical compositions of said compounds and the use of said pharmaceutical compositions to treat or prevent viral infections. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of viral disorders and pathologic conditions such as, but not limited to, viral infections with Human Immunodeficiency Virus 1 (HIV1), Human Immunodeficiency Virus 2 (HIV2), Hepatitis C virus (HCV), Dengue virus, and enteroviruses like Coxsackievirus, Rhinovirus and Poliovirus.