215929-27-4

Basic information

• Product Name: (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one
• Synonyms: (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one
• CAS NO: 215929-27-4
• Molecular Weight: 491.587
• Mol File: 215929-27-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one(215929-27-4)
• EPA Substance Registry System: (R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one(215929-27-4)

Safety Data

• Hazardous Substances Data: 215929-27-4(Hazardous Substances Data)

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 102-92-1 Cinnamoyl chloride 
• 140-10-3 (E)-3-phenylacrylic acid 
• 146235-33-8 (R)-3-cinnamoyl-4-phenyloxazolidin-2-one 
• 2830-53-7 1-(benzyloxy)-2-bromo-4-methylbenzene 
• 155835-37-3 (4R)-3-(3-phenyl-2-(E)-propenoyl)-4-phenyl-2-oxazolidinone 

Downstream Products

• 827007-19-2 (R)-6-methyl-4-phenyl-3,4-dihydrochromen-2-one 
• 1191280-45-1 (R)-3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropanoyl chloride 
• 1191280-47-3 (R)-3-(2-(benzyloxy)-5-methylphenyl)-N,N-di(isopropyl-d7)-3-phenylpropan-1-amine 
• 1191280-46-2 (R)-3-(2-(benzyloxy)-5-methylphenyl)-N,N-di(isopropyl-d7)-3-phenylpropanamide 
• 1191280-48-4 (R)-2-(3-(di(isopropyl-d7)amino)-1-phenylpropyl)-4-methylphenol L-tartrate 
• 215929-29-6 (R)-3-(2-Benzyloxy-5-methyl-phenyl)-N,N-diisopropyl-3-phenyl-propionamide 
• 124937-51-5 (R)-(+)-tolterodine 
• 215929-28-5 (R)-3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropanoic acid 

Relevant articles and documents

Conjugate addition of aryl nucleophiles to α,β-unsaturated cinnamic acid derivatives containing Evans type chiral auxiliaries

Cinnamides containing oxazolidin-2-one type auxiliaries have been prepared. A novel pathway to chiral 4-aryl-6-methyl-3,4-dihydrocoumrines via the asymmetric conjugate addition of arylmagnesium bromides to these cinnamides is described.

Asymmetric total synthesis of (+)-tolterodine, a new muscarinic receptor antagonist, via copper-assisted asymmetric conjugate addition of aryl Grignard reagents to 3-phenyl-prop-2-enoyl-oxazolidinones

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