216019-59-9

Basic information

• Product Name: neomenthyldiphenylphosphine
• Synonyms: neomenthyldiphenylphosphine
• CAS NO: 216019-59-9
• Molecular Weight: 324.446
• Mol File: 216019-59-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: neomenthyldiphenylphosphine(CAS DataBase Reference)
• NIST Chemistry Reference: neomenthyldiphenylphosphine(216019-59-9)
• EPA Substance Registry System: neomenthyldiphenylphosphine(216019-59-9)

Safety Data

• Hazardous Substances Data: 216019-59-9(Hazardous Substances Data)

Upstream product

• 61548-81-0 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl methanesulfonate 

Downstream Products

• 22071-15-4 ketoprofen 

Relevant articles and documents

Production of high purity alkali metal diarylphosphide and cycloalkyldiarylphosphines

(1) Alkali metal diarylphosphides are formed by mixing triarylphosphine with, and preferably introducing triarylphosphine into, a two-phase mixture one or more alkali metals, preferably a mixture or alloy of sodium and potassium, in an anhydrous organic l

Synthesis of cycloalkyldiarylphosphines

Partially sterically-hindered cycloalkyl chlorides are reacted with lithium diarylphosphides in inert liquid hydrocarbon reaction media to form cycloalkyldiarylphosphines. Aryl lithium is coproduced. The process makes it possible to avoid, or at least substantially eliminate, the interaction with or cleavage of cyclic ether reaction media such as tetrahydrofuran, previously the solvent of choice for conducting this type of reaction. Also during the conduct of the present process the chloro-substituted cycloalkane does not undergo any appreciable reaction with the coproduced aryl lithium as it is formed. Thus improvements both in yield and quality of the cycloalkyldiarylphosphine product are made possible. A comprehensive three-step process for converting triarylphosphine to cycloalkyldiarylphosphine is also described.