2161-87-7 Usage
Description
2,4,6-Triacetylphloroglucinol (TAPG) is a hydrophobic small molecular weight phenolic metabolite belonging to the phloroglucinol family, produced by bacteria such as Pseudomonas strains. It is a C3-symmetric tritopic bridging ligand and exhibits a broad range of biological activities, although mostly with low potency. TAPG is characterized by its beige needle-like appearance.
Uses
Used in Organic Synthesis:
2,4,6-Triacetylphloroglucinol is used as a compound in organic synthesis for the creation of various complex organic molecules.
Used in Pharmaceutical Industry:
2,4,6-Triacetylphloroglucinol is used as a precursor in the synthesis of trinuclear vanadium Schiff base complexes, copper complexes, and anthelmintics, contributing to the development of pharmaceutical agents.
Used in Biocontrol of Plant Diseases:
Although weakly active, 2,4,6-Triacetylphloroglucinol and related metabolites are important in the biocontrol of plant diseases by some Pseudomonas strains, playing a role in dereplication to eliminate leads with high amounts of weakly potent actives.
Preparation
Obtained by Friedel–Crafts acylation of phloroglucinol, ? with acetic anhydride in the presence of boron trifluoride in acetic acid at r.t. (60%) ; ? with acetyl chloride in the presence of aluminium chloride in ethyl ether at r.t. for 6 days (17%); ? with acetyl chloride and acetic acid in the presence of ferric chloride in ethyl acetate.
Check Digit Verification of cas no
The CAS Registry Mumber 2161-87-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,6 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2161-87:
(6*2)+(5*1)+(4*6)+(3*1)+(2*8)+(1*7)=67
67 % 10 = 7
So 2161-87-7 is a valid CAS Registry Number.
2161-87-7Relevant articles and documents
Use of a hexasubstituted benzene scaffold in the development of multivalent HIV-1 integrase inhibitors
Tupchiangmai, Wipa,Choksakulporn, Saowanaporn,Tewtrakul, Supinya,Pianwanit, Somsak,Sritana-Anant, Yongsak
, p. 754 - 763 (2014)
The highly directional hexasubstituted benzene moiety was used as the central scaffold to create new human immunodeficiency virus (HIV)-1 integrase inhibitors through the attachment of multiple active groups. A series of potential inhibitors having substi
Three-metal-center Schiff base-aluminium compound, preparation method, application and preparation method of polylactic acid
-
Paragraph 0105; 0108, (2017/03/08)
The invention provides a three-metal-center Schiff base-aluminium compound, which has a structure as shown in the formula (I). By using triacetyl-m-trihydroxybenzene as the core, a three-metal active center binding site is provided to form three-metal-cen
Selective fries rearrangement catalyzed by zinc powder
Paul, Satya,Gupta, Monika
, p. 1789 - 1792 (2007/10/03)
Zinc powder in the presence of N,N-dimethylformamide efficiently catalyzes the selective Fries rearrangement of acetylated phenols under microwave heating or with conventional heating using an oil bath. In some cases different products were obtained using microwave heating and conventional heating. Selective migration of the acyl group has been noted with good yields.
