21637-25-2 Usage
Description
ISOQUERCITRIN, also known as Isoquercitroside, is a flavonoid compound found within medicinal plants. It is a quercetin O-glucoside in which a glucofuranosyl residue is attached at position 3 of quercetin via a beta-glycosidic linkage. ISOQUERCITRIN is known for its various biological activities, including the inhibition of adipocyte differentiation. It is reported to be found in Gossypium spp. and is available in the form of a yellow powder or white to dark yellow powder, which is odorless.
Uses
Used in Pharmaceutical Industry:
ISOQUERCITRIN is used as a bioactive compound for its various biological activities, including the inhibition of adipocyte differentiation. This property makes it a potential candidate for the development of drugs targeting obesity and related metabolic disorders.
Used in Nutraceutical Industry:
ISOQUERCITRIN is used as a natural ingredient in the nutraceutical industry due to its health-promoting properties. Its presence in medicinal plants and its biological activities contribute to the development of dietary supplements and functional foods that aim to improve overall health and well-being.
Used in Cosmetic Industry:
ISOQUERCITRIN, with its various biological activities, can be used as an active ingredient in the cosmetic industry. It may be incorporated into skincare products for its potential anti-inflammatory, antioxidant, and anti-aging properties, contributing to improved skin health and appearance.
Used in Research and Development:
ISOQUERCITRIN is used as a subject of study in research and development for its potential applications in various fields, such as pharmaceuticals, nutraceuticals, and cosmetics. Its biological activities and properties make it an interesting compound for further investigation and potential development of new products and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 21637-25-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,3 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 21637-25:
(7*2)+(6*1)+(5*6)+(4*3)+(3*7)+(2*2)+(1*5)=92
92 % 10 = 2
So 21637-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1
21637-25-2Relevant articles and documents
Preparation of isoquercitrin by biotransformation of rutin using α-L-rhamnosidase from Aspergillus niger JMU-TS528 and HSCCC purification
Li, Li Jun,Liu, Xiao Qing,Du, Xi Ping,Wu, Ling,Jiang, Ze Dong,Ni, Hui,Li, Qing Biao,Chen, Feng
, p. 1 - 9 (2020)
Isoquercitrin is a flavonoid with important applications in the pharmaceutical and nutraceutical industries. However, a low yield and high production cost hinders the industrial preparation of isoquercitrin. In the present study, isoquercitrin was prepared by biotransformation of rutin using α-L-rhamnosidase from Aspergillus niger JMU-TS528 combined with high-speed countercurrent chromatography (HSCCC) purification. As a result, the optimum transformation pH, temperature, and time were pH 4.0, 60 °C, and 60 min, respectively. The Km and Vmax were 0.36 mM and 0.460 mmol/min, respectively. For isoquercitrin production, the optimal rutin concentration and transformation time were approximately 1000 mg/L and 60 min. The rutin transformation rate reached 96.44%. The isoquercitrin was purified to a purity of 97.83% using one-step purification with HSCCC. The isoquercitrin was identified using UPLC-Q-TOF-MS. The comprehensive results indicated that the biotransformation procedure using the α-L-rhamnosidase from A. niger JMU-TS528 combined with HSCCC was a simple and effective process to prepare isoquercitrin, which might facilitate the production of isoquercitrin for industrial use.