216393-55-4

Basic information

• Product Name: METHYL 3,5-DIFLUOROBENZOATE
• Synonyms: BUTTPARK 89\07-67;METHYL 3,5-DIFLUOROBENZOATE;RARECHEM AL BF 0216;3,5-Difluorobenzoic acid methyl ester;Methyl 3,5-difluorobenzoate 98%;Methyl3,5-difluorobenzoate98%;Methyl 3,5-difluorobenzoate LR Grade
• CAS NO: 216393-55-4
• Molecular Formula: C8H6F2O2
• Molecular Weight: 172.13
• EINECS: -0
• Product Categories: Aromatic Esters;C8 to C9;Carbonyl Compounds;Esters
• Mol File: 216393-55-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 23-27 °C(lit.)
• Boiling Point: 187-189 °C(lit.)
• Flash Point: 170 °C
• Appearance: /
• Density: 1.265 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.288mmHg at 25°C
• Refractive Index: n20/D 1.4740(lit.)
• Storage Temp.: Room temperature.
• CAS DataBase Reference: METHYL 3,5-DIFLUOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3,5-DIFLUOROBENZOATE(216393-55-4)
• EPA Substance Registry System: METHYL 3,5-DIFLUOROBENZOATE(216393-55-4)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22
• Safety Statements: 36
• WGK Germany: 3
• Hazardous Substances Data: 216393-55-4(Hazardous Substances Data)

Usage

General Description

METHYL 3,5-DIFLUOROBENZOATE is a chemical compound with the molecular formula C8H6F2O2. It is a colorless liquid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. METHYL 3,5-DIFLUOROBENZOATE is often used as a building block in organic synthesis and can also be found in some cosmetic and personal care products. It is important to handle this chemical with care and follow proper safety protocols, as it can be hazardous if not used properly.

InChI:InChI=1/C8H6F2O2/c1-12-8(11)5-2-6(9)4-7(10)3-5/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 455-40-3 3,5-difluorobenzoic acid 

Downstream Products

• 181697-20-1 1-(3,5-difluorophenyl)-2-phenylethanone 
• 1384445-22-0 N-(4-(4-(3,5-difluorobenzyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide-(D₂) 
• 1384448-26-3 C₁₁H₁₂⁽²⁾H₂F₂N₂*ClH 
• 1384448-25-2 C₁₆H₂₀⁽²⁾H₂F₂N₂O₂ 
• 1384448-24-1 C₈H₆⁽²⁾H₂F₂O₃S 
• 1620579-73-8 dideutero(3,5-difluorophenyl)methanol 
• 1620567-92-1 4-(4-methylpiperazin-1-yl)-6-(3,5-difluorophenyl)-1,3,5-triazin-2-amine 
• 1249074-73-4 C₁₀H₈F₂O 

Relevant articles and documents

Method for manufacturing triarylpyrazine derivative

A novel synthesis method of a triarylpyrazine derivative, in particular, a manufacturing method by which a triarylpyrazine derivative, in specific, a 2,3,5-triarylpyrazine derivative in which an aryl group at a 5-position includes a substituent having an electron-withdrawing property can be synthesized with high yield as compared to a conventional method is provided. By using a synthesis method in which a mixture including a 1-aryl-2-(methylsulfinyl)ethanone derivative, meso-1,2-diarylethylenediamine, and a dehydrogenation agent is irradiated with a microwave to be reacted, the above object is achieved.

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.