2164-93-4Relevant articles and documents
Room-temperature palladium-catalyzed C-H activation: Ortho-carbonylation of aniline derivatives
Houlden, Chris E.,Hutchby, Marc,Bailey, Chris D.,Ford, J.Gair,Tyler, Simon N. G.,Gagne, Michel R.,Lloyd-Jones, Guy C.,Booker-Milburn, Kevin I.
supporting information; experimental part, p. 1830 - 1833 (2009/08/07)
Pd and CO - ureally got me! The title reaction proceeds efficiently at 18°C under CO (1 atm) with 5 % [Pd(OTs)2 (MeCN)2] as precatalyst. Depending on the solvents used, either anthranilates or cyclic imides can be obtained in high yields (see picture, BQ=benzoquinone, Ts=4-toluenesulfonyl).
