21654-18-2

Basic information

• Product Name: 1,4-diethyl 2-benzylsuccinate
• CAS NO: 21654-18-2
• Molecular Weight: 264.321
• Mol File: 21654-18-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,4-diethyl 2-benzylsuccinate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-diethyl 2-benzylsuccinate(21654-18-2)
• EPA Substance Registry System: 1,4-diethyl 2-benzylsuccinate(21654-18-2)

Safety Data

• Hazardous Substances Data: 21654-18-2(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 36092-42-9 2-benzylsuccinic acid 
• 25952-53-8 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride 
• 1520-50-9 but-2-enedioic acid diethyl ester 
• 100-51-6 benzyl alcohol 
• 42201-84-3 1-ethoxy-1-(tert-butyldimethylsilyloxy)ethene 
• 2021-28-5 ethyl dihydrocinnamate 
• 58195-50-9 ethyl (E)-4-phenyl-3-ethoxycarbonyl-3-enoate 
• 123-25-1 succinic acid diethyl ester 
• 78173-73-6 diethyl (Z)-2-benzylidenesuccinate 

Downstream Products

• 21654-17-1 (R)-2-benzyl-4-ethoxy-4-oxobutanoic acid 
• 21307-94-8 diethyl (S)-2-benzylsuccinate 
• 943321-35-5 diethyl 2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-2-(phenylmethyl)butanedioate 
• 21307-97-1 (R)-2-benzylsuccinic acid 
• 3972-36-9 (2S)-benzylsuccinic acid 

Relevant articles and documents

New heterogenized gold(I)-heterocyclic carbene complexes as reusable catalysts in hydrogenation and cross-coupling reactions

Mononuclear unsymmetrical N-heterocyclic carbene-gold complexes and the corresponding solid catalysts in which a gold-carbene complex has been immobilized on silica gel, ordered mesoporous silica (MCM-41), and delaminated zeolite (ITQ-2) have been prepared. These new catalysts have been tested in the hydrogenation of alkenes and the Suzuki cross-coupling reaction to afford selectively non-symmetrical biaryls. These reactions were studied with the soluble as well as with the heterogenized counterpart catalysts. The high accessibility introduced by the structure of the supports allows the preparation of highly efficient immobilized catalysts with TOFs up to 400 h-1. Moreover, the heterogenized complexes were reused and no deactivation of the catalysts can be observed.

Vanadium(V)-Induced Oxidative Cross-Coupling of Various Boron and Silyl Enolates

Intermolecular oxidative cross-coupling of two different enolates is one of the most useful reactions to synthesize unsymmetrical 1,4-dicarbonyl compounds. In this study, the oxovanadium(V)-induced intermolecular oxidative cross-coupling of enolates afforded unsymmetrical 1,4-dicarbonyl compounds. Various boron and silyl enolates underwent the formation of ketone–ester, ester–ketone, ester–ester, amide–ketone and amide–ester coupling products. These results clearly show the versatility of the present oxidative cross-coupling protocol.

First pre-functionalised polymeric aromatic framework from mononitrotetrakis(iodophenyl)methane and its applications

Starting from mononitrotetrakis(iodophenyl)methane as monomer, we report the preparation of the first pre-functionalised porous aromatic frameworks (PAFs) and their application as supports for organometallic catalysts. Neutral coordinate imino-pyridine Schiff base (PAF-NPy) or chiral bis-amino (PAF-NPro) ligands were obtained by post-synthetic treatment of PAF-NH2 and treated with copper(I) or rhodium(I) to yield the corresponding supported transition-metal catalysts. The as-prepared PAF-NN-M catalysts exhibited activity and selectivity similar to that of the corresponding homogeneous catalysts and were easily removed from reaction media and recycled without loss of activity or selectivity. New copper catalysts: The preparation of pre-functionalised porous aromatic frameworks (PAFs) and their application as supports for organometallic catalysts (see figure) is reported for the first time.