21658-35-5

Basic information

• Product Name: 3-naphthalen-2-ylpropanoic acid
• Synonyms: 3-naphthalen-2-ylpropanoic acid;3-Naphthalen-2-yl-propionicacid;3-(β-NAPHTHYL)-PROPIONIC ACID;2-Naphthalenepropanoic acid;3-(BETA-NAPHTHYL)-PROPIONIC ACID
• CAS NO: 21658-35-5
• Molecular Formula: C₁₃H₁₂O₂
• Molecular Weight: 200.23
• Mol File: 21658-35-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 134-135 °C(Solv: ethanol (64-17-5))
• Boiling Point: 382.339 °C at 760 mmHg
• Flash Point: 279.199 °C
• Appearance: /
• Density: 1.195 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.633
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.57±0.10(Predicted)
• CAS DataBase Reference: 3-naphthalen-2-ylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-naphthalen-2-ylpropanoic acid(21658-35-5)
• EPA Substance Registry System: 3-naphthalen-2-ylpropanoic acid(21658-35-5)

Safety Data

• Hazardous Substances Data: 21658-35-5(Hazardous Substances Data)

Usage

General Description

3-Naphthalen-2-ylpropanoic acid is a chemical compound that belongs to the class of organic compounds known as naphthalenes, which are characterized by a two fused ring system of carbon atoms. This particular chemical is composed of a propanoic acid group attached to a naphthalene unit at the 2nd position. Propanoic acid (also known as propionic acid) is a three-carbon carboxylic acid, while naphthalene is a polycyclic aromatic hydrocarbon (PAH) made up of two benzene rings fused together. As a specific compound, 3-naphthalen-2-ylpropanoic acid may be utilized in variety of applications, including research and development, chemical synthesis or as a reference standard. Its physicochemical properties, such as solubility or melting point, depend on its exact molecular structure and may vary accordingly.

InChI:InChI=1/C13H12O2/c14-13(15)8-6-10-5-7-11-3-1-2-4-12(11)9-10/h1-5,7,9H,6,8H2,(H,14,15)

Upstream product

• 61705-42-8 p-nitrophenyl-3-(2-naphthyl)-propionate 
• 111200-27-2 α-acetyl-3-(2-naphthalenyl)propionic acid ethyl ester 
• 51257-26-2 4-trimethylammonio-6-nitrophenyl-3-(2-naphthyl)-propionate iodide 
• 61705-40-6 3-(3-Naphthalen-2-yl-propionyloxy)-4-nitro-benzoic acid anion 
• 82178-01-6 3β-amino-17β-(4'-imidazolyl)-5α-androstan-11-one 
• 82177-95-5 α,α'-bis(17β-(4'-imidazolyl)-11-keto-5α-androstan-3β-amino)-p-xylene 
• 288-32-4 1H-imidazole 
• 1592-38-7 2-Naphthalenemethanol 
• 21473-01-8 2-naphthalenylmagnesium bromide 

Downstream Products

• 1616119-53-9 ethyl 2-(3-(naphthalen-2-yl)propanamido)cyclohex-1-enecarboxylate 
• 61705-42-8 p-nitrophenyl-3-(2-naphthyl)-propionate 
• 136415-67-3 3-(naphthalen-2-yl)propanal 
• 7475-48-1 δ-(Naphthyl-2)-valeriansaeure 
• 1618094-37-3 C₂₀H₁₅IN₂O 
• 1618095-20-7 N-hydroxy-3-(4-(5-(2-(2-naphthyl)ethyl)-1,3,4-oxadiazol-2-yl)phenyl)acrylamide 
• 1618094-80-6 C₂₃H₁₈N₂O₃ 
• 1618094-59-9 C₂₇H₂₆N₂O₃ 
• 136534-58-2 1-phenyl-4-[3-(2-naphthyl)propyl]piperazine 
• 175881-65-9 (1S,3aS,9bR)-trans-(-)-1-benzoyloxy-3a,9b-epoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[g]indene 

Relevant articles and documents

Aromatic Claisen Rearrangements of Benzyl Ketene Acetals: Conversion of Benzylic Alcohols to (ortho-Tolyl)acetates

Claisen rearrangements of benzyl vinyl ethers are much less facile than those of aliphatic allyl vinyl ethers, and their synthetic utility has remained relatively unexplored. A one-pot procedure is reported for the generation and Claisen rearrangement of benzyl vinyl ethers that contain an activating α-alkoxy substituent on the vinyl group. A [3,3]-sigmatropic mechanism was supported by trapping of the intermediate isotoluene in an intramolecular Alder–ene reaction.

Large hydrophobic interactions with clearly defined geometry. A dimeric steroid with catalytic properties.

The steroid dimer α,α'-bis(17β-(4'-imidazolyl)-11-keto-5α-androstan-3β-amino)-p-xylene, 3, has been synthesized by reductive amination of 17β-(4'-imidazolyl)-5α-androstane-3,11-dione by p-xylenediamine in the presence of sodium cyanoborohydride, and by reductive amination of terephthalaldehyde by 3β-amino-17β-(4'-imidazolyl)-5α-androstan-11-one.The second method is stereochemically unambiguous; the first is not.Compound 3 acts as a catalyst for the hydrolysis of 3-arylpropionate esters of 3-hydroxy-4-nitrobenzoic acid.For the phenanthryl propionate the rateenhancement relative to imidazole is 200-fold, and the rate enhancement relative to the hypothetical rate for the propionate reacting with the steroid by the same transition state geometry is 3000-fold.The slope of a plot kkorr vs. ? for the reaction of 3b with aryl propionate ester was 0.83; the corresponding slope for 12 was 0.39.This provides a design parameter for the construction of artificial enzymes.