21668-99-5 Usage
Classification
Sulfone
The compound belongs to a class of organic compounds that contain a sulfonyl group (-SO2-) bonded to an aromatic ring.
Benzene ring structure
The compound consists of a benzene ring, which is a six-carbon ring with alternating single and double bonds.
Methyl group at the 1 position
A methyl group (-CH3) is attached to the benzene ring at the first carbon atom position.
Sulfonyl group attached to 4-methylbenzyl
A sulfonyl group (-SO2-) is bonded to a 4-methylbenzyl group, which is itself attached to the benzene ring.
Use as a building block in organic synthesis
The compound is often used as a starting material or intermediate in the synthesis of more complex organic molecules.
Application in the pharmaceutical industry
It is commonly used in the production of various pharmaceuticals due to its versatile chemical structure.
Potential applications in agrochemicals and other organic compounds
The compound may also be used in the synthesis of agrochemicals and other organic compounds, such as dyes, pigments, and polymers.
Utilization in research and development
It may be employed in research and development settings for the creation of novel molecules and materials with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 21668-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,6 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21668-99:
(7*2)+(6*1)+(5*6)+(4*6)+(3*8)+(2*9)+(1*9)=125
125 % 10 = 5
So 21668-99-5 is a valid CAS Registry Number.
21668-99-5Relevant articles and documents
Synthesis of sulfone derivatives via palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides
Luo, Jin,Wan, Juelin,Wang, Tao,Yu, Weijie
supporting information, (2021/12/31)
A palladium-catalyzed cross-coupling of benzyl trimethylammonium triflates and sulfonyl hydrazides for the synthesis of various benzyl sulfones is reported. This novel protocol shows widespread functional group tolerance, leading to the desired sulfones in moderate to excellent yields.
Vanadium-catalyzed Selective Oxidation of Sulfides to Sulfoxides and Sulfones with H2O2
Chen, M.,Jia, A.-Q.,Zhang, P.-Z.,Zhang, Q.-F.,Zhou, W.-Y.
, p. 816 - 824 (2021/06/12)
Abstract: A direct selective approach to the oxidation of sulfides to sulfoxides andsulfones with H2O2 in moderate togood yields is developed. The reaction proceeds in the presence of 2 mol % ofVO(acac)2 at room temperature. All sulfoxides andsulfones were detected by gas chromatography, and the molecular structures of2-methylbenzyl 4-methylphenyl sulfone, 4-methylbenzyl 4-methylphenyl sulfone,2-bromobenzyl 4-methylphenyl sulfone, and 4-tert-butylbenzyl benzyl sulfone were determined by singlecrystal X-ray crystallography.
Visible-Light-Catalyzed in Situ Denitrogenative Sulfonylation of Sulfonylhydrazones
Huang, Xiang,Chen, Xing,Xie, Haisheng,Tan, Zheng,Jiang, Huanfeng,Zeng, Wei
, p. 6784 - 6788 (2021/09/08)
A photocatalyzed in situ denitrogenative sulfonylation of N-arylsulfonyl hydrazones has been developed. This transformation provides a low-carbon strategy to assemble arylalkyl sulfones in a stepwise denitrogenation/sulfonylation manner.
