2167-14-8

Basic information

• Product Name: 1-Ethyl-1H-pyrrole-2-carbaldehyde
• Synonyms: 1-Ethyl-1H-pyrrole-2-carbaldehyde;1-Ethyl-1H-pyrrole-2-carboxaldehyde;1-ethyl-1H-pyrrole-2-carbaldehyde (SALTDATA: FREE);1-ETHYL-2-PYRROLECARBOXALDEHYDE
• CAS NO: 2167-14-8
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• Mol File: 2167-14-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 59 °C(Press: 6 Torr)
• Appearance: /
• Density: 0.99±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: -6.88±0.70(Predicted)
• Stability: Moisture Sensitive
• CAS DataBase Reference: 1-Ethyl-1H-pyrrole-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Ethyl-1H-pyrrole-2-carbaldehyde(2167-14-8)
• EPA Substance Registry System: 1-Ethyl-1H-pyrrole-2-carbaldehyde(2167-14-8)

Safety Data

• Hazardous Substances Data: 2167-14-8(Hazardous Substances Data)

Usage

General Description

1-Ethyl-1H-pyrrole-2-carbaldehyde, also known as 1-Ethylpyrrole-2-carboxaldehyde, is a chemical compound with the molecular formula C8H11NO. This organic compound appears as a transparent orange liquid which is highly soluble in water. It falls under the category of pyrroles and pyrrole derivatives, which are polycyclic aromatic compounds containing a pyrrole ring. 1-Ethyl-1H-pyrrole-2-carbaldehyde has potential use in the pharmaceutical and chemical industries for intermediates and synthesis. As with all chemicals, it should be handled with care to ensure safety, as it might be harmful if ingested or comes into contact with skin.

Upstream product

• 1192-58-1 N-methylpyrrole aldehyde 
• 74-88-4 methyl iodide 
• 1003-29-8 2-pyrrole aldehyde 
• 78-40-0 triethyl phosphate 
• 90005-94-0 3-(2-formyl-1H-pyrrol-1-yl)propanoic acid 
• 20948-40-7 methyl 3-(2-formyl-1H-pyrrol-1-yl)propanoate 
• 75-03-6 ethyl iodide 
• 1708-41-4 2-(furan-2-yl)-1,3-dioxolane 
• 98-01-1 furfural 
• 74-96-4 ethyl bromide 
• 400715-57-3 phenyl 3-(2-formyl-1H-pyrrol-1-yl)propaneselenoate 
• 400715-78-8 1-(2-Bromoethyl)-1H-pyrrole-2-carbaldehyde 
• 617-92-5 1-ethyl-1H-pyrrole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1590409-43-0 C₁₆H₁₃F₃N₂O₂ 
• 26116-12-1 1-ethyl-2-pyrrolidinemethanamine 

Relevant articles and documents

-

-

Preparation method for N-ethyl-2-aminomethylpyrrolidine

The invention relates to a preparation method for N-ethyl-2-aminomethylpyrrolidine. The preparation method comprises the following steps: with furfural as a raw material, subjecting the furfural to acetal protection so as to obtain furfural glycol acetal, allowing the furfural glycol acetal to react with ethylamine so as to generate 2-(1,3-dioxolan-2-yl)-N-ethylpyrrole, allowing the 2-(1,3-dioxolan-2-yl)-N-ethylpyrrole to react with diluted hydrochloric acid so as to generate N-ethylpyrrole-2-carbaldehyde, and subjecting the N-ethylpyrrole-2-carbaldehyde and liquid ammonia to palladium-carbonreductive ammoniation by one step so as to generate the N-ethyl-2-aminomethylpyrrolidine. The preparation method has a synthetic route which is described in the specification. The invention has the following advantages: the preparation method for the N-ethyl-2-aminomethylpyrrolidine provided by the invention starts with the furfural as a raw material to prepare a product through protection, amination and reductive ammoniation, and has the advantages of short reaction route, high yield capable of reaching 85% or above, little pollution and applicability to industrialization.

Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast

New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping