216974-96-8Relevant articles and documents
Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting
Malcor, Jean-Daniel,Payrot, Nadine,David, Marion,Faucon, Aude,Abouzid, Karima,Jacquot, Guillaume,Floquet, Nicolas,Debarbieux, Franck,Rougon, Geneviève,Martinez, Jean,Khrestchatisky, Michel,Vlieghe, Patrick,Lisowski, Vincent
, p. 2227 - 2241 (2012)
Drug delivery to the central nervous system is hindered by the presence of physiological barriers such as the blood-brain barrier. To accomplish the task of nutrient transport, the brain endothelium is endowed with various transport systems, including rec