216984-82-6Relevant articles and documents
Dithiocarbamate promoted practical synthesis of N-Aryl-2-aminobenzazoles: Synthesis of novel Aurora-A kinase inhibitor
Katari, Naresh Kumar,Venkatanarayana,Srinivas, Kummari
, p. 447 - 453 (2015)
Various N-aryl-2-aminobenzoxazoles and N-aryl-2-aminobenzothiazoles were synthesized from o-aminophenol and o-aminothiophenol, respectively, mediated by dithiocarbamate in one step. The salient features of this method include mild reaction condition, high
Water-Mediated Synthesis of Benzazole and Thiourea Motifs by Reacting Naturally Occurring Isothiocyanate with Amines
Sharma, Ritika,Bala, Manju,Verma, Praveen Kumar,Singh, Bikram
supporting information, p. 2106 - 2114 (2015/09/01)
An efficient, green, and facile method has been developed for the synthesis of benzazole and thiourea analogues from naturally occurring erucin in moderate to good yields. The reaction was carried out in water without using any metal catalyst or base. The present method tolerated the various functional groups on aromatic rings and also applicable for other isothiocyanates.
An economically and environmentally sustainable synthesis of 2-aminobenzothiazoles and 2-aminobenzoxazoles promoted by water
Zhang, Xinying,Jia, Xuefei,Wang, Jianji,Fan, Xuesen
supporting information; experimental part, p. 413 - 418 (2011/04/16)
Tandem reactions of isothiocyanates (1) with 2-aminothiophenols (2), or isothiocyanates (1) with 2-aminophenols (4), were carried out rapidly and efficiently in water. A significant rate acceleration of the reaction between 1a and 2a in water compared wit